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Nervosine
Nervosine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Nervosine
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CAS No.: 23179-26-2
Catalog No.: CFN00300
Molecular Formula: C36H53NO12
Molecular Weight: 691.81 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Liparis nervosa
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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Description: Reference standards.
Nervosine Description
Source: The herbs of Liparis nervosa
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4455 mL 7.2274 mL 14.4548 mL 28.9097 mL 36.1371 mL
5 mM 0.2891 mL 1.4455 mL 2.891 mL 5.7819 mL 7.2274 mL
10 mM 0.1445 mL 0.7227 mL 1.4455 mL 2.891 mL 3.6137 mL
50 mM 0.0289 mL 0.1445 mL 0.2891 mL 0.5782 mL 0.7227 mL
100 mM 0.0145 mL 0.0723 mL 0.1445 mL 0.2891 mL 0.3614 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Chemical Letters, 2016,27(5):757-760.
Three new pyrrolizidine alkaloids derivatives from Liparis nervosa.[Reference: WebLink]

METHODS AND RESULTS:
Three new pyrrolizidine alkaloids, Nervosine VII (1), Nervosine VIII (2) and Nervosine IX (3) were isolated from the whole plant extract of Liparis nervosa. Their structures were elucidated by extensive spectroscopic analyses (including 1D, 2D NMR, and HR-ESI-MS) and chemical methods.
CONCLUSIONS:
Compounds 1–3 were evaluated for their cytotoxic activity against A549, MCF-7and H460 human cancer cell lines.
CFN00289Lasiocarpine303-34-4411.49C21H33NO7
CFN00290Lasiocarpine N-oxide127-30-0427.49C21H33NO8
CFN00298Paludosine34137-24-1559.69C31H45NO8
CFN00299Kumokirine21284-20-8574.73C32H48NO8+
CFN00300Nervosine23179-26-2691.81C36H53NO12
CFN00301Auriculine22595-00-2559.70C31H45NO8
CFN00302Phalaenopsine T23412-97-7361.44C20H27NO5
CFN00303Phalaenopsine La23412-99-9361.44C20H27NO5
CFN00304Phalaenopsine Is41451-64-3361.44C20H27NO5
CFN00305Procerine68622-81-1271.31C13H21NO5
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