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Nortropacocaine
Nortropacocaine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Nortropacocaine
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CAS No.: 18470-33-2
Catalog No.: CFN00171
Molecular Formula: C14H17NO2
Molecular Weight: 231.29 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Helicia lobata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Nortropacocaine Description
Source: The herbs of Helicia lobata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3236 mL 21.6179 mL 43.2358 mL 86.4715 mL 108.0894 mL
5 mM 0.8647 mL 4.3236 mL 8.6472 mL 17.2943 mL 21.6179 mL
10 mM 0.4324 mL 2.1618 mL 4.3236 mL 8.6472 mL 10.8089 mL
50 mM 0.0865 mL 0.4324 mL 0.8647 mL 1.7294 mL 2.1618 mL
100 mM 0.0432 mL 0.2162 mL 0.4324 mL 0.8647 mL 1.0809 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Pharm Sci. 1979 Jun;68(6):788-90.
Nortropacocaine hydrochloride conformation in aqueous and hydrophobic media.[Pubmed: 458585]
The Nortropacocaine hydrochloride PMR spectra in deuterium oxide and in deuterochloroform differed markedly.
METHODS AND RESULTS:
A detailed conformational analysis using vicinal 1H-1H coupling constants revealed the molecular conformation to be identical in both solvents. The preferred conformation was one in which the piperidine component existed as a deformed chair. The spectral differences were due to a decreased deshielding of the protonated nitrogen on the neighboring bicyclic ring protons, resulting in chemical shift changes.
CFN00148Anisodine52646-92-1319.36C17H21NO5
CFN00149Apoatropine500-55-0271.36C17H21NO2
CFN00150Apohyoscine535-26-2285.34C17H19NO3
CFN00151Aponorhyoscine25650-56-0271.31C16H17NO3
CFN00171Nortropacocaine18470-33-2231.29C14H17NO2
CFN00177Bellendine32152-73-1205.26C12H15NO2
CFN00181Brugine14912-30-2273.42C12H19NO2S2
CFN00182Chalcostrobamine75638-72-1269.34C17H19NO2
CFN00183Cocaine50-36-2303.35C17H21NO4
CFN00184Pseudococaine478-73-9303.35C17H21NO4
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Procyanidin B3

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