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O-Methylcedrelopsin
O-Methylcedrelopsin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name O-Methylcedrelopsin
Price:
CAS No.: 72916-61-1
Catalog No.: CFN92731
Molecular Formula: C16H18O4
Molecular Weight: 274.3 g/mol
Purity: >=98%
Type of Compound: Coumarins
Physical Desc.: Cryst.
Source: The roots of Toddalia asiatica Lam.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: O-Methylcedrelopsin may have vasorelaxing activity.
In vitro:
Planta Med. 2003 Feb;69(2):179-81.
Vasorelaxing properties and bio-guided fractionation of Cedrelopsis grevei.[Pubmed: 12624830]

METHODS AND RESULTS:
The activity-guided fractionation of the hydroalcoholic extract of trunk bark of Cedrelopsis grevei led to the isolation of five coumarins, norbraylin (1), methyl-O-cedrelopsin (O-Methylcedrelopsin,2), cedrecoumarin A (3), scoparone (4) and braylin (5) as a part of the constituents responsible for the vasorelaxing activity observed for the crude extract.
O-Methylcedrelopsin Description
Source: The roots of Toddalia asiatica Lam.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6456 mL 18.2282 mL 36.4564 mL 72.9129 mL 91.1411 mL
5 mM 0.7291 mL 3.6456 mL 7.2913 mL 14.5826 mL 18.2282 mL
10 mM 0.3646 mL 1.8228 mL 3.6456 mL 7.2913 mL 9.1141 mL
50 mM 0.0729 mL 0.3646 mL 0.7291 mL 1.4583 mL 1.8228 mL
100 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.7291 mL 0.9114 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry. 2002 Dec;61(8):919-22.
Coumarins from Cedrelopsis grevei (Ptaeroxylaceae).[Pubmed: 12453517]

METHODS AND RESULTS:
The stem bark of Cedrelopsis grevei Baill. has yielded the first reported examples of 5-prenylated coumarins, cedrecoumarin A and B as well as the known coumarins, cedrelopsin, scoparone, O-Methylcedrelopsin and norbraylin, and the known chromones ptaeroglycol and ptaeroxylinol.
CFN98505Murrayone19668-69-0258.27C15H14O4
CFN99090Isomeranzin1088-17-1260.3 C15H16O4
CFN98994Meranzin hydrate5875-49-0278.3 C15H18O5
CFN993628-(3-Ethoxy-2-hydroxy-3-methylbutyl)-7-methoxycoumarin 125072-68-6306.4 C17H22O5
CFN89410Cedrelopsin19397-28-5260.28C15H16O4
CFN92731O-Methylcedrelopsin72916-61-1274.3C16H18O4
CFN99811Coumurrayin17245-25-9274.3 C16H18O4
CFN97531Sibiricin95188-34-4290.3 C16H18O5
CFN97454Isomexoticin88585-86-8308.3 C16H20O6
CFN99097Murraol109741-38-0260.3 C15H16O4
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