Science | Nature | Cell | View More
Natural Products
Ophiopogonanone E
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ophiopogonanone E
Price:
CAS No.: 588706-66-5
Catalog No.: CFN96332
Molecular Formula: C19H20O7
Molecular Weight: 360.4 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The tubers of Ophiopogon japonicus(Thunb) Ker-Gawl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Nanjing University of Chinese M... (China)
  • University of Medicine and Phar... (Romania)
  • University of Hawaii Cancer Center (USA)
  • University of Auckland (New Zealand)
  • Weizmann Institute of Science (Israel)
  • University of Maryland School o... (USA)
  • Universit?t Basel (Switzerland)
  • Florida A&M University (USA)
  • University Medical Center Mainz (Germany)
  • Chinese University of Hong Kong (China)
  • University of Mysore (India)
  • More...
Package
Featured Products
Ginsenoside Rh1

Catalog No: CFN99970
CAS No: 63223-86-9
Price: $60/20mg
Coumarin

Catalog No: CFN99552
CAS No: 91-64-5
Price: $30/20mg
Sinigrin

Catalog No: CFN90453
CAS No: 3952-98-5
Price: $80/20mg
Stigmasterol glucoside

Catalog No: CFN98000
CAS No: 19716-26-8
Price: $368/5mg
Salicylic acid

Catalog No: CFN93274
CAS No: 69-72-7
Price: $30/20mg
Quercetin 3-O-neohesperidoside

Catalog No: CFN91148
CAS No: 32453-36-4
Price: $318/10mg
trans-3-Hydroxycinnamic acid

Catalog No: CFN98181
CAS No: 14755-02-3
Price: $30/20mg
Alpha-caryophyllene

Catalog No: CFN93582
CAS No: 6753-98-6
Price: $40/20mg
Asiaticoside B

Catalog No: CFN95124
CAS No: 125265-68-1
Price: $158/20mg
L-Glutamic acid

Catalog No: CFN93108
CAS No: 56-86-0
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
In vitro:
Chinese Journal of Natural Medicines,2008,6(3):201-4.
Homoisoflavonoids from Ophiopogon japonicus and Its Oxygen Free Radicals(OFRs) Scavenging Effects[Pubmed: 12444717]
To investigate the OFRs scavenging activities of homoisoflavonoids from the fibrous root of Ophiopogon japonicus.
METHODS AND RESULTS:
The scavenging effect of homoisoflavonoids isolated from O.japonicus extracts was examined on superoxide anion(O2·-),hydroxyl radical(·OH),and hydrogen peroxide(H2O2) by chemiluminescence.Ten homoisoflavonoids were obtained from O.japonicus extracts.They were identified as methylophiopogonanone A(1),methylophiopogonanone B(2),ophiopogonanone A(3),Ophiopogonanone E(4),5,7-dihydroxy-6,8-dimethyl-3-(4'-hydroxy-3',5'-methoxybenzyl) chroman-4-one(5),methylophiopogonone A(6),methylophiopogonone B(7),desmethylisoophiopogonone B(8),5,7,2'-trihydroxy-8-methyl-3-(3',4'-methylenedioxybenzyl) chromone(9) and 5,7,2'-trihydroxy-6,8-dimethyl-3-(3',4'-methylenedioxybenzyl) chromone(10).
CONCLUSIONS:
Compounds 8 and 9 were firstly isolated from O.japonicus.The majority of homoisoflavonoids could scavenge ·OH and H2O2 in vitro to a certain extent,and their bioactivities should be related with the respective structures.
Ophiopogonanone E Description
Source: The tubers of Ophiopogon japonicus(Thunb) Ker-Gawl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Cannabisin M

Catalog No: CFN95436
CAS No: 1831134-13-4
Price: $318/5mg
N1,N5,N10-(Z)-tri-p-coumaroylsperm...

Catalog No: CFN95253
CAS No: 131086-78-7
Price: $238/5mg
1,2-Epoxy-10(14)-furanogermacren-6...

Catalog No: CFN95214
CAS No: 383368-24-9
Price: $318/10mg
Quercetin 3-O-beta-(6''-p-coumaroy...

Catalog No: CFN95088
CAS No: 143061-65-8
Price: $338/10mg
N-Demethylfordianoside

Catalog No: CFN95589
CAS No: N/A
Price: $318/10mg
6''-O-Acetylsaikosaponin D

Catalog No: CFN95090
CAS No: 64340-45-0
Price: $288/5mg
Annphenone

Catalog No: CFN95426
CAS No: 61775-18-6
Price: $318/10mg
Cannabisin B

Catalog No: CFN95268
CAS No: 144506-17-2
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7747 mL 13.8735 mL 27.7469 mL 55.4939 mL 69.3674 mL
5 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
10 mM 0.2775 mL 1.3873 mL 2.7747 mL 5.5494 mL 6.9367 mL
50 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
100 mM 0.0277 mL 0.1387 mL 0.2775 mL 0.5549 mL 0.6937 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 2002 Nov;65(11):1731-3.
Five new homoisoflavonoids from the tuber of Ophiopogon japonicus[Pubmed: 12444717]

METHODS AND RESULTS:
Five new homoisoflavonoids, ophiopogonanone C (1), ophiopogonanone D (2), ophiopogonone C (3), Ophiopogonanone E (4) and ophiopogonanone F (5), and six known compounds were isolated from an ethanol extract of the tubers of Ophiopogon japonicus (Thunb) Ker-Gawl. Spectroscopic analyses were used to elucidate the structures of these compounds.
Ginsenoside Rh1

Catalog No: CFN99970
CAS No: 63223-86-9
Price: $60/20mg
Coumarin

Catalog No: CFN99552
CAS No: 91-64-5
Price: $30/20mg
Sinigrin

Catalog No: CFN90453
CAS No: 3952-98-5
Price: $80/20mg
Stigmasterol glucoside

Catalog No: CFN98000
CAS No: 19716-26-8
Price: $368/5mg
Salicylic acid

Catalog No: CFN93274
CAS No: 69-72-7
Price: $30/20mg
Quercetin 3-O-neohesperidoside

Catalog No: CFN91148
CAS No: 32453-36-4
Price: $318/10mg
trans-3-Hydroxycinnamic acid

Catalog No: CFN98181
CAS No: 14755-02-3
Price: $30/20mg
Alpha-caryophyllene

Catalog No: CFN93582
CAS No: 6753-98-6
Price: $40/20mg
Asiaticoside B

Catalog No: CFN95124
CAS No: 125265-68-1
Price: $158/20mg
L-Glutamic acid

Catalog No: CFN93108
CAS No: 56-86-0
Price: $30/20mg
Tags: buy Ophiopogonanone E | Ophiopogonanone E supplier | purchase Ophiopogonanone E | Ophiopogonanone E cost | Ophiopogonanone E manufacturer | order Ophiopogonanone E | Ophiopogonanone E distributor