Science | Nature | Cell | View More
Natural Products
Phyllostine
Phyllostine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Phyllostine
Price:
CAS No.: 27270-89-9
Catalog No.: CFN97901
Molecular Formula: C7H6O4
Molecular Weight: 154.1 g/mol
Purity: >=98%
Type of Compound: Quinones
Physical Desc.: Yellow powder
Source: From Pencillium urticae
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universidad de Antioquia (Colombia)
  • University of Canterbury (New Zealand)
  • University of Fribourg (Switzerland)
  • Universidad Miguel Hernández (Spain)
  • Kamphaengphet Rajabhat University (Thailand)
  • Anna University (India)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • University of Dicle (Turkey)
  • Instytut Nawozów Sztucznych w ... (Poland)
  • Michigan State University (USA)
  • University of Ioannina (Greece)
  • More...
Package
Featured Products
Sinigrin

Catalog No: CFN90453
CAS No: 3952-98-5
Price: $80/20mg
Dauricine

Catalog No: CFN98129
CAS No: 524-17-4
Price: $98/20mg
2,3,2'',3''-Tetrahydroochnaflavone

Catalog No: CFN97157
CAS No: 678138-59-5
Price: $ /
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Sakakin

Catalog No: CFN98059
CAS No: 21082-33-7
Price: $40/20mg
beta-Amyrin acetate

Catalog No: CFN99679
CAS No: 1616-93-9
Price: $ /
Delta 5-avenasterol

Catalog No: CFN92239
CAS No: 18472-36-1
Price: $413/5mg
Lithospermic acid

Catalog No: CFN98546
CAS No: 28831-65-4
Price: $138/20mg
Phytic acid

Catalog No: CFN99792
CAS No: 83-86-3
Price: $40/20mg
Betaine

Catalog No: CFN99546
CAS No: 107-43-7
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Phyllostine appears to be their more immediate precursor, since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these new metabolites.
Phyllostine Description
Source: From Pencillium urticae
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Vicinin 2

Catalog No: CFN95249
CAS No: 90456-53-4
Price: $368/5mg
Isonemerosin

Catalog No: CFN95008
CAS No: 181524-79-8
Price: $268/20mg
(1E)-3-methoxy-8,12-epoxygermacra-...

Catalog No: CFN95219
CAS No: 1393342-06-7
Price: $413/5mg
Benzyl beta-D-glucopyranoside

Catalog No: CFN95427
CAS No: 4304-12-5
Price: $318/10mg
Methyl neochebulinate

Catalog No: CFN95201
CAS No: 1236310-34-1
Price: $398/5mg
New compound 7

Catalog No: CFN95330
CAS No: N/A
Price: $368/5mg
Hosenkoside L

Catalog No: CFN95520
CAS No: N/A
Price: $318/10mg
Pterodonoic acid

Catalog No: CFN95183
CAS No: 62458-42-8
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.4893 mL 32.4465 mL 64.8929 mL 129.7859 mL 162.2323 mL
5 mM 1.2979 mL 6.4893 mL 12.9786 mL 25.9572 mL 32.4465 mL
10 mM 0.6489 mL 3.2446 mL 6.4893 mL 12.9786 mL 16.2232 mL
50 mM 0.1298 mL 0.6489 mL 1.2979 mL 2.5957 mL 3.2446 mL
100 mM 0.0649 mL 0.3245 mL 0.6489 mL 1.2979 mL 1.6223 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Can J Microbiol. 1979 Aug;25(8):881-7.
Patulin biosynthesis: the metabolism of phyllostine and isoepoxydon by cell-free preparations from Pencillium urticae.[Pubmed: 43192]

METHODS AND RESULTS:
Cell-free extracts of Penicillium urticae (NRRL 2159A), and its Pat- mutants, J2, J1, and S11, were found to contain significant NADP-dependent isoepoxydon dehydrogenase activity. This reversible interconversion of the epoxides (-)-Phyllostine and (+)-isoepoxydon occurred optimally at pH 5.8 and was completely inhibited by 1 mM p-chloromercuribenzoate (PCMB). The cytosol enzyme possessed specificity for both substrate and cofactor since neither (+)-epoxydon, an epimer of (+)-isoepoxydon, nor NADH was utilized. Cell extracts of the parent and of mutant J2, which is blocked before the epoxides in the patulin pathway, were found to convert Phyllostine and isoepoxydon to a number of unknown metabolites which appeared as yellow spots on thin-layer chromatograms after spraying with a chromogenic reagent. Extracts of mutant J1 were unable to carry out this conversion, while whole cells of mutant S11 accumulated what appeared to be these same 'yellow' compounds.
CONCLUSIONS:
Since PCMB-treated extracts of J2 converted Phyllostine but not isoepoxydon to these new metabolites, Phyllostine appeared to be their more immediate precursor. The relative positions of isoepoxydon and Phyllostine in the patulin pathway are discussed.
Sinigrin

Catalog No: CFN90453
CAS No: 3952-98-5
Price: $80/20mg
Dauricine

Catalog No: CFN98129
CAS No: 524-17-4
Price: $98/20mg
2,3,2'',3''-Tetrahydroochnaflavone

Catalog No: CFN97157
CAS No: 678138-59-5
Price: $ /
3,9-Dihydroxypterocarpan

Catalog No: CFN97043
CAS No: 61135-91-9
Price: $ /
Sakakin

Catalog No: CFN98059
CAS No: 21082-33-7
Price: $40/20mg
beta-Amyrin acetate

Catalog No: CFN99679
CAS No: 1616-93-9
Price: $ /
Delta 5-avenasterol

Catalog No: CFN92239
CAS No: 18472-36-1
Price: $413/5mg
Lithospermic acid

Catalog No: CFN98546
CAS No: 28831-65-4
Price: $138/20mg
Phytic acid

Catalog No: CFN99792
CAS No: 83-86-3
Price: $40/20mg
Betaine

Catalog No: CFN99546
CAS No: 107-43-7
Price: $30/20mg
Tags: buy Phyllostine | Phyllostine supplier | purchase Phyllostine | Phyllostine cost | Phyllostine manufacturer | order Phyllostine | Phyllostine distributor