Science | Nature | Cell | View More
Natural Products
Phyperunolide E
Phyperunolide E
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Phyperunolide E
Price:
CAS No.: 1198400-52-0
Catalog No.: CFN96990
Molecular Formula: C28H40O9
Molecular Weight: 520.61 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The fruits of Physalis peruviana L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Subang Jaya Medical Centre (Malaysia)
  • Hamdard University (India)
  • Johannes Gutenberg University M... (Germany)
  • Universita' Degli Studi Di Cagl... (Italy)
  • Deutsches Krebsforschungszentrum (Germany)
  • University of Eastern Finland (Finland)
  • National Chung Hsing University (Taiwan)
  • Uniwersytet Medyczny w ?odzi (Poland)
  • University of Cincinnati (USA)
  • Univerzita Karlova v Praze (Czech Republic)
  • University of Brasilia (Brazil)
  • More...
Package
Featured Products
Acetylshikonin

Catalog No: CFN90523
CAS No: 24502-78-1
Price: $138/20mg
Dehydromiltirone

Catalog No: CFN98532
CAS No: 116064-77-8
Price: $438/5mg
(-)-Epicatechin gallate

Catalog No: CFN99570
CAS No: 1257-08-5
Price: $40/20mg
Kaempferol 3-O-arabinoside

Catalog No: CFN97572
CAS No: 99882-10-7
Price: $338/5mg
25S-Inokosterone

Catalog No: CFN93571
CAS No: 19595-18-7
Price: $318/10mg
Tiliroside

Catalog No: CFN98026
CAS No: 20316-62-5
Price: $70/20mg
3,4-Dihydroxybenzoic acid

Catalog No: CFN97568
CAS No: 99-50-3
Price: $30/20mg
L-Glutamic acid

Catalog No: CFN93108
CAS No: 56-86-0
Price: $30/20mg
Ganoderic acid G

Catalog No: CFN90801
CAS No: 98665-22-6
Price: $318/20mg
Decursinol

Catalog No: CFN90496
CAS No: 23458-02-8
Price: $238/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Phyperunolide E is a natural product from Physalis peruviana L.
In vitro:
Food Chemistry, 2009, 116(2):462-469.
New cytotoxic withanolides from Physalis peruviana.[Reference: WebLink]

METHODS AND RESULTS:
Investigation of the extracts of Physalis peruviana L. has led to the isolation of seven new withanolides, phyperunolide A (1), phyperunolide B (2), phyperunolide C (3), phyperunolide D (4), peruvianoxide (5), Phyperunolide E (16), and phyperunolide F (17) together with ten known withanolides. The structure and absolute stereochemistry of all compounds were elucidated on the basis of CD and NMR spectral analysis, respectively.
CONCLUSIONS:
Compounds 1, 6, 7, and 9 showed cytotoxicity against lung cancer (A549), breast cancer (MDA-MB-231 and MCF7), and liver cancer (Hep G2 and Hep 3B) cancer cell lines. The presence of 5β,6β-epoxy-2-en-1-ones in withanolides is greatly helpful in cytotoxicity, it is a key known important factor to cytotoxicity; however, interestingly, the unusual 5-chloride withanolide, 9, displayed significant activity.
Phyperunolide E Description
Source: The fruits of Physalis peruviana L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Aegineoside

Catalog No: CFN95270
CAS No: 752209-48-6
Price: $413/5mg
Nortrachelogenin-8'-O-beta-glucosi...

Catalog No: CFN95234
CAS No: 858127-38-5
Price: $368/10mg
3''-O-Galloylmyricitrin

Catalog No: CFN95057
CAS No: 143202-36-2
Price: $333/5mg
Quercetin 3,5-O-diglucoside

Catalog No: CFN95486
CAS No: 206257-35-4
Price: $368/10mg
Ganolucidic acid E

Catalog No: CFN95536
CAS No: 114567-50-9
Price: $318/5mg
Isorhamnetin-3-O-rutinoside-7-O-gl...

Catalog No: CFN95494
CAS No: 55481-91-9
Price: $318/5mg
Dehydrodicatechin A

Catalog No: CFN95451
CAS No: 36048-23-4
Price: $318/5mg
Meliotocarpan D

Catalog No: CFN95401
CAS No: 83013-81-4
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9208 mL 9.6041 mL 19.2082 mL 38.4165 mL 48.0206 mL
5 mM 0.3842 mL 1.9208 mL 3.8416 mL 7.6833 mL 9.6041 mL
10 mM 0.1921 mL 0.9604 mL 1.9208 mL 3.8416 mL 4.8021 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7683 mL 0.9604 mL
100 mM 0.0192 mL 0.096 mL 0.1921 mL 0.3842 mL 0.4802 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Acetylshikonin

Catalog No: CFN90523
CAS No: 24502-78-1
Price: $138/20mg
Dehydromiltirone

Catalog No: CFN98532
CAS No: 116064-77-8
Price: $438/5mg
(-)-Epicatechin gallate

Catalog No: CFN99570
CAS No: 1257-08-5
Price: $40/20mg
Kaempferol 3-O-arabinoside

Catalog No: CFN97572
CAS No: 99882-10-7
Price: $338/5mg
25S-Inokosterone

Catalog No: CFN93571
CAS No: 19595-18-7
Price: $318/10mg
Tiliroside

Catalog No: CFN98026
CAS No: 20316-62-5
Price: $70/20mg
3,4-Dihydroxybenzoic acid

Catalog No: CFN97568
CAS No: 99-50-3
Price: $30/20mg
L-Glutamic acid

Catalog No: CFN93108
CAS No: 56-86-0
Price: $30/20mg
Ganoderic acid G

Catalog No: CFN90801
CAS No: 98665-22-6
Price: $318/20mg
Decursinol

Catalog No: CFN90496
CAS No: 23458-02-8
Price: $238/20mg
Tags: buy Phyperunolide E | Phyperunolide E supplier | purchase Phyperunolide E | Phyperunolide E cost | Phyperunolide E manufacturer | order Phyperunolide E | Phyperunolide E distributor