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Pseudotropine
Pseudotropine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Pseudotropine
Price: $40 / 20mg
CAS No.: 135-97-7
Catalog No.: CFN00217
Molecular Formula: C8H15NO
Molecular Weight: 141.21 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Atropa belladonna.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.
In vivo:
Vet. Hum. Toxicol., 1995, 37(5):452-4
Toxicity of field bindweed (Convolvulus arvensis) to mice.[Pubmed: 8592835]
The effects of feeding high and low doses of field bindweed (Convolvulus arvensis) to mice were investigated. Bindweed contains several alkaloids, including Pseudotropine, and lesser amounts of tropine, tropinone, and meso-cuscohygrine.
METHODS AND RESULTS:
Mice fed bindweed exclusively died or were euthanized after 4-7 d and had severe hepatic necrosis and gastritis with ulceration or erosions. Mice fed low doses of bindweed along with standard laboratory mouse diet for 6 or 8 w had no clinical disease or gross lesions on necropsy examination but did have histologic lesions of mild multifocal hepatitis and gastritis.
Pseudotropine Description
Source: The roots of Atropa belladonna.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.0817 mL 35.4083 mL 70.8165 mL 141.633 mL 177.0413 mL
5 mM 1.4163 mL 7.0817 mL 14.1633 mL 28.3266 mL 35.4083 mL
10 mM 0.7082 mL 3.5408 mL 7.0817 mL 14.1633 mL 17.7041 mL
50 mM 0.1416 mL 0.7082 mL 1.4163 mL 2.8327 mL 3.5408 mL
100 mM 0.0708 mL 0.3541 mL 0.7082 mL 1.4163 mL 1.7704 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron Letters Volume 25, Issue 44, 1984, Pages 5091–5094
A new synthetic route to tropane alkaloids. Pseudotropine and tropacocaine[Reference: WebLink]
Pseudotropine and tropacocaine have been synthesized by a facile route involving the [4 + 2] nitroso cycloaddition followed by internal SN2 displacement.
CFN00205Tropine120-29-6141.21C8H15NO
CFN00206Tropine acetate3423-27-6183.25C10H17NO2
CFN00207Tropine isobutyrate495-80-7211.30C12H21NO2
CFN00209Tropine nonanoate146018-90-8281.44C17H31NO2
CFN00217Pseudotropine135-97-7141.21C8H15NO
CFN002183-Acetoxytropane3423-26-5183.25C10H17NO2
CFN00220Tropinone532-24-1139.19C8H13NO
CFN004776-Hydroxytropinone5932-53-6155.2C8H13NO2
CFN00221Physoperuvine60723-27-5141.21C8H15NO
CFN00226Scopine498-45-3155.20C8H13NO2
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