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Raddeanoside 20
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Raddeanoside 20
Price: $238 / 5mg
CAS No.: 335354-79-5
Catalog No.: CFN90659
Molecular Formula: C47H76O17
Molecular Weight: 913.1 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The rhizomes of Anemone raddeana Regel
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $346.5 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Raddeanoside 20 can slightly suppress the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) in a concentration dependent manner.
In vitro:
Fitoterapia. 2009 Mar;80(2):105-11.
Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeana.[Pubmed: 19084054]
Four triterpenoid compounds hederacolchiside E (1), hederasaponin B (2), Raddeanoside 20 (3) and raddeanoside 21 (4) were isolated from ethanol extracts of rhizome of Anemone raddeana Regel.
METHODS AND RESULTS:
The effects of these triterpenoids on superoxide generation, tyrosyl phosphorylation of proteins and translocation of cytosolic compounds, such as p47(phox), p67(phox) and Rac to the cell membrane in human neutrophils was investigated. The superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP) was slightly suppressed by hederasaponin B, Raddeanoside 20 and raddeanoside 21 in a concentration dependent manner. The superoxide generation induced by arachidonic acid (AA) was suppressed by hederasaponin B and raddeanoside 21 significantly.
CONCLUSIONS:
fMLP- and AA-induced tyrosyl phosphorylation and translocation of the cytosolic proteins: p47(phox), p67(phox), and Rac to the cell membrane were suppressed in parallel with the suppression of stimulus-induced superoxide generation.
Raddeanoside 20 Description
Source: The rhizomes of Anemone raddeana Regel
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0952 mL 5.4759 mL 10.9517 mL 21.9034 mL 27.3793 mL
5 mM 0.219 mL 1.0952 mL 2.1903 mL 4.3807 mL 5.4759 mL
10 mM 0.1095 mL 0.5476 mL 1.0952 mL 2.1903 mL 2.7379 mL
50 mM 0.0219 mL 0.1095 mL 0.219 mL 0.4381 mL 0.5476 mL
100 mM 0.011 mL 0.0548 mL 0.1095 mL 0.219 mL 0.2738 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $40/20mg
1-Dehydro-6-gingerdione

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Price: $258/10mg
Protodioscin

Catalog No: CFN99517
CAS No: 55056-80-9
Price: $50/20mg
1,2,3,4,6-O-Pentagalloylglucose

Catalog No: CFN90192
CAS No: 14937-32-7
Price: $80/20mg
Cantharidin

Catalog No: CFN99790
CAS No: 56-25-7
Price: $40/20mg
Jaceosidin

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CAS No: 18085-97-7
Price: $168/20mg
Cyanidin-3-O-galactoside chloride

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Price: $318/10mg
Schisantherin D

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Isosaponarin

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Price: $318/10mg
6beta-Hydroxystigmast-4-en-3-one

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