Rauvovertine A | CAS:2055073-75-9 | Manufacturer ChemFaces

Rauvovertine A

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Rauvovertine A Description

Source:	The stems of Rauvolfia verticillata.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Fitoterapia. 2015 Dec;107:44-48.

Hexacyclic monoterpenoid indole alkaloids from Rauvolfia verticillata.[Pubmed: 26474672 ]

METHODS AND RESULTS:
Five new hexacyclic monoterpenoid indole alkaloids, Rauvovertine A (1), 17-epi-Rauvovertine A (2), Rauvovertine B (3), 17-epi-Rauvovertine B (4), and rauvovertine C (5) together with 17 known analogues were isolated from the stems of Rauvolfia verticillata. Compounds 1/2 and 3/4 were obtained as C-17 epimeric mixtures due to rapid hemiacetal tautomerism in solution.
CONCLUSIONS:
The structures of 1-5 were established by spectroscopic analysis and with the aid of molecular modeling. The new alkaloids were evaluated for their cytotoxicity in vitro against human tumor HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.

Product Name	Rauvovertine A
Price:
CAS No.:	2055073-75-9
Catalog No.:	CFN89451
Molecular Formula:	C₁₉H₂₂N₂O₃
Molecular Weight:	326.38 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The stems of Rauvolfia verticillata.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0639 mL	15.3196 mL	30.6391 mL	61.2783 mL	76.5978 mL
5 mM	0.6128 mL	3.0639 mL	6.1278 mL	12.2557 mL	15.3196 mL
10 mM	0.3064 mL	1.532 mL	3.0639 mL	6.1278 mL	7.6598 mL
50 mM	0.0613 mL	0.3064 mL	0.6128 mL	1.2256 mL	1.532 mL
100 mM	0.0306 mL	0.1532 mL	0.3064 mL	0.6128 mL	0.766 mL

CFN98684	10-Hydroxydihydroperaksine	451478-47-0	328.4	C₁₉H₂₄N₂O₃
CFN98712	N-Methylsarpagine methosalt	47418-70-2	339.5	C₂₁H₂₇N₂O₂
CFN98759	Sarpagine	482-68-8	310.4	C₁₉H₂₂N₂O₂
CFN98852	Lochnerine	522-47-4	324.4	C₂₀H₂₄N₂O₂
CFN99240	(Z)-Akuammidine	113973-31-2	352.4	C₂₁H₂₄N₂O₃
CFN99677	Dihydroperaksine	16100-84-8	312.4	C₁₉H₂₄N₂O₂
CFN99655	Peraksine	15527-80-7	310.4	C₁₉H₂₂N₂O₂
CFN89449	Rauvovertine B	2055073-72-6	326.38	C₁₉H₂₂N₂O₃
CFN89450	Rauvovertine C	2055073-74-8	321.41	C₂₀H₂₃N₃O
CFN89451	Rauvovertine A	2055073-75-9	326.38	C₁₉H₂₂N₂O₃