Scutebata E | CAS:1207181-61-0 | Manufacturer ChemFaces

Scutebata E

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Description:

Scutebata E shows weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines.

In vitro:

J Asian Nat Prod Res. 2013 Sep;15(9):941-9.

Bioassay-guided isolation of neo-clerodane diterpenoids from Scutellaria barbata.[Pubmed: 23909895]

METHODS AND RESULTS:
Bioassay-guided isolation of the aerial part of Scutellaria barbata yielded three new neo-clerodane diterpenoids scutebatas P-R (1-3), together with two known ones: Scutebata E (4) and scutebarbatine B (5). The chemical structures of the isolated compounds were elucidated by spectroscopic methods (NMR and MS) and by comparison with the spectroscopic data reported in the literature.
CONCLUSIONS:
All compounds except 3 showed weak cytotoxicity with IC50 values ranging from 35.11 to 42.73 μM against K562 cell lines, and compounds 1, 2, and 5 also displayed weak activities against HL60 cell lines.

Scutebata E Description

Source:	The herbs of Scutellaria barbata D.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Scutebata E
Price:
CAS No.:	1207181-61-0
Catalog No.:	CFN99325
Molecular Formula:	C₂₈H₄₀O₉
Molecular Weight:	520.6 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The herbs of Scutellaria barbata D.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9209 mL	9.6043 mL	19.2086 mL	38.4172 mL	48.0215 mL
5 mM	0.3842 mL	1.9209 mL	3.8417 mL	7.6834 mL	9.6043 mL
10 mM	0.1921 mL	0.9604 mL	1.9209 mL	3.8417 mL	4.8022 mL
50 mM	0.0384 mL	0.1921 mL	0.3842 mL	0.7683 mL	0.9604 mL
100 mM	0.0192 mL	0.096 mL	0.1921 mL	0.3842 mL	0.4802 mL

CFN99326	Scutebata F	1207181-62-1	555.6	C₃₀H₃₇NO₉
CFN99327	Scutebata G	1207181-63-2	679.8	C₄₀H₄₁NO₉
CFN96994	6-O-Nicotinoylscutebarbatine G	1206805-30-2	576.64	C₃₂H₃₆N₂O₈
CFN96705	Scutebarbatine W	1312716-25-8	575.65	C₃₃H₃₇NO₈
CFN97783	2-Oxokolavelool	221466-41-7	304.47	C₂₀H₃₂O₂
CFN97792	Kolavenol	19941-83-4	290.49	C₂₀H₃₄O
CFN97832	2-Oxokolavenol	130395-82-3	304.47	C₂₀H₃₂O₂
CFN96984	16-Oxocleroda-3,13E-dien-15-oic acid	117620-72-1	318.45	C₂₀H₃₀O₃
CFN98262	Monomethyl kolavate	24513-41-5	348.5	C₂₁H₃₂O₄
CFN99325	Scutebata E	1207181-61-0	520.6	C₂₈H₄₀O₉