| In vitro: |
| Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9. | | Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme.[Pubmed: 15997133] | Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7).
METHODS AND RESULTS:
Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively. | | Chem Biodivers. 2008 Jul;5(7):1419-24. | | Biflavanones, flavonoids, and coumarins from the roots of Stellera chamaejasme and their antiviral effect on hepatitis B virus.[Pubmed: 18649308 ] | A new 3,3''-biflavanone, isoSikokianin A, was isolated from the roots of Stellera chamaejasme, together with eleven known compounds.
METHODS AND RESULTS:
Their structures and configurations were elucidated by spectroscopic methods including 2D-NMR techniques. Sikokianin A, chamaechromone, and quercetin showed in vitro antiviral activity against HBsAg secretion. |
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