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Styraxlignolide F
Styraxlignolide F
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Styraxlignolide F
Price:
CAS No.: 823214-06-8
Catalog No.: CFN92491
Molecular Formula: C27H34O11
Molecular Weight: 534.6 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The herbs of Styrax japonica
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Styraxlignolide F is a natural product from Styrax japonica.
In vitro:
J Nat Prod. 2004 Dec;67(12):1980-4.
New furofuran and butyrolactone lignans with antioxidant activity from the stem bark of Styrax japonica.[Pubmed: 15620237]
A new furofuran lignan, styraxlignolide B (1), and four new dibenzyl-gamma-butyrolactone lignans, styraxlignolides C, styraxlignolide D, styraxlignolide E, and Styraxlignolide F (2-5), were isolated from the EtOAc-soluble fraction of stem bark of Styrax japonica.
METHODS AND RESULTS:
Known compounds, taraxerol (6), syringin (7), and (-)-pinoresinol glucoside (8), were also obtained. The structures of styraxligonolides B-F were determined as 2alpha-(4'-hydroxy-3'-methoxyphenyl)-6alpha-(3' ',4' '-methylenedioxyphenyl)-8-oxo-3,7-dioxabicyclo[3.3.0]octane 4'-O-(beta-D-glucopyranoside) (1), (2S,3S)-2alpha-(3' '-hydroxy-4' '-methoxybenzyl)-3beta-(4'-hydroxy-3'-methoxybenzyl)-gamma-butyrolactone 4'-O-(beta-D-glucopyranoside) (2), (2S,3S)-2alpha-(4' '-hydroxy-3' '-methoxybenzyl)-3beta-(4'-hydroxy-3'-methoxybenzyl)-gamma-butyrolactone 4'-O-(beta-D-glucopyranoside) (3), (2S,3S)-2alpha-(4' '-hydroxy-3' '-methoxybenzyl)-3beta-(4'-hydroxy-3'-methoxybenzyl)-gamma-butyrolactone 4' '-O-(beta-D-glucopyranoside) (4), and (2S,3S)-2alpha-(3' ',4' '-dimethoxybenzyl)-3beta-(4'-hydroxy-3'-methoxybenzyl)-gamma-butyrolactone 4'-O-(beta-D-glucopyranoside) (5) by spectroscopic means including 2D NMR.
CONCLUSIONS:
Compounds 1-8 were tested in vitro for antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Styraxlignolide C (2), styraxlignolide D (3), styraxlignolide E (4), and (-)-pinoresinol glucoside (8) exhibited weak radical-scavenging activity in the DPPH assay, with IC50 values of 380, 278, 194, and 260 microM, respectively.
Styraxlignolide F Description
Source: The herbs of Styrax japonica
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8706 mL 9.3528 mL 18.7056 mL 37.4111 mL 46.7639 mL
5 mM 0.3741 mL 1.8706 mL 3.7411 mL 7.4822 mL 9.3528 mL
10 mM 0.1871 mL 0.9353 mL 1.8706 mL 3.7411 mL 4.6764 mL
50 mM 0.0374 mL 0.1871 mL 0.3741 mL 0.7482 mL 0.9353 mL
100 mM 0.0187 mL 0.0935 mL 0.1871 mL 0.3741 mL 0.4676 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN95068Lappaol C64855-00-1554.6C30H34O10
CFN95225Isolappaol C929905-15-7554.6C30H34O10
CFN95069Lappaol F69394-17-8714.8C40H42O12
CFN96715(+)-Matairesinol148409-36-3358.39C20H22O6
CFN96234Isosalicifolin156974-99-1356.4C20H20O6
CFN98454Nortrachelogenin34444-37-6374.4 C20H22O7
CFN96714(+)-Nortrachelogenin61521-74-2374.38C20H22O7
CFN89300(7R)-Methoxy-8-epi-matairesinol198827-23-5388.41C21H24O7
CFN90598Trachelogenin34209-69-3388.15C21H24O7
CFN93080Nortracheloside33464-78-7536.53C26H32O12
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