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Triacetonamine
Triacetonamine
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Product Name Triacetonamine
Price: $30 / 20mg
CAS No.: 826-36-8
Catalog No.: CFN97315
Molecular Formula: C9H17NO
Molecular Weight: 155.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Solid
Source: The herbs of Salsola tetrandra
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Triacetonamine protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK); it also inhibits CaCl2 induced agglomeration of thromocyte. Triacetonamine can improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles.
Targets: SOD | MDA
In vitro:
Bioresour Technol. 2010 Jun;101(11):4242-5.
Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent.[Pubmed: 20137920]
A sewage sludge sample was pyrolyzed in a drop tube furnace at 500 degrees C and sweeping gas flow rate of 300cm(3)/min.
METHODS AND RESULTS:
Triacetonamine (TAA) was detected with GC/MS as major component in the resulting bio-oil using acetone as the absorption solvent and proven to be a product from the reaction of NH(3) in the bio-oil with the absorption solvent acetone. TAA yield increased with storage time and reached a level about 28.4% (% sludge fed, daf) after 175h. Since the reaction of pure NH(3) with acetone does not proceed, some species in the bio-oil must catalyze the reaction of NH(3) with acetone. TAA was isolated in a high yield (27.9%, daf) and high purity (80.4%) by column chromatography with different solvents, including mixed solvents, as eluants.
CONCLUSIONS:
The study revealed the possibility of sewage sludge as potential resource of TAA.
Supplement to the Journal of Sun Yatsen University, 1994 (6) :9-11.
Protective Effects of Triacetonamine on Acute Ischemia Isolated Rat Heart Muscles[Reference: WebLink]
Triacetonamine(TAA)could improve the constructile function of heart mus-cles of acute anemia and decrease the content of malodialdehyde (MDA) in the heart muscles. TAA protects the activitis of superoxide dismutase(SOD) and creatine phos-phate kinase (CPK). It also inhibits CaCl2 induced agglomeration of thromocyte.
Triacetonamine Description
Source: The herbs of Salsola tetrandra
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.4433 mL 32.2165 mL 64.433 mL 128.866 mL 161.0825 mL
5 mM 1.2887 mL 6.4433 mL 12.8866 mL 25.7732 mL 32.2165 mL
10 mM 0.6443 mL 3.2216 mL 6.4433 mL 12.8866 mL 16.1082 mL
50 mM 0.1289 mL 0.6443 mL 1.2887 mL 2.5773 mL 3.2216 mL
100 mM 0.0644 mL 0.3222 mL 0.6443 mL 1.2887 mL 1.6108 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Comput Aided Mol Des. 1990 Dec;4(4):403-9.
Theoretical models for the conformations and the protonation of triacetonamine.[Pubmed: 1965442]
In this paper we propose theoretical models for the conformations of Triacetonamine and protonated Triacetonamine (Vincubine, an anticancer chemotherapeutic agent) developed by quantum and molecular mechanics techniques.
METHODS AND RESULTS:
We discuss the theoretical factors which are involved in the stabilization of the conformations calculated by the MNDO, MM2 and COPEANE methods and show the relative percent abundance of each molecular shape. Graphic representations of the conformers are depicted.
CFN98649(+)-N-Methylallosedridine41447-16-9157.3 C9H19NO
CFN99627Calyxamine B150710-72-8195.3 C12H21NO
CFN99865Methylisopelletierine18747-42-7155.2 C9H17NO
CFN90870Tetrahydropiperin23434-88-0289.4C17H23NO3
CFN95683Piperanine23512-46-1287.4C17H21NO3
CFN99919Piperine94-62-2285.34C17H19NO3
CFN91467Piperyline25924-78-1271.3C16H17NO3
CFN95678Pipernonaline88660-10-0341.5C21H27NO3
CFN95691Dehydropipernonaline107584-38-3339.4C21H25NO3
CFN95664Methyl piperate6190-46-1232.2C13H12O4
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