Science | Nature | Cell | View More
Natural Products
Ursonic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ursonic acid
Price: $50 / 20mg
CAS No.: 6246-46-4
Catalog No.: CFN97078
Molecular Formula: C30H46O3
Molecular Weight: 454.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The dried fruit of Ziziphus jujuba.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $12.7 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universidad de Ciencias y Artes... (Mexico)
  • Universita' Degli Studi Di Cagl... (Italy)
  • Chulalongkorn University (Thailand)
  • Molecular Biology Institute of ... (Spain)
  • University of the Basque Country (Spain)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Copenhagen University (Denmark)
  • University of Parma (Italy)
  • Stanford University (USA)
  • University of Hawaii Cancer Center (USA)
  • Michigan State University (USA)
  • More...
Package
Featured Products
Angelicin

Catalog No: CFN98854
CAS No: 523-50-2
Price: $30/20mg
DL-Syringaresinol

Catalog No: CFN99276
CAS No: 1177-14-6
Price: $ /
Glycyrin

Catalog No: CFN89404
CAS No: 66056-18-6
Price: $368/5mg
Oxyresveratrol

Catalog No: CFN98368
CAS No: 29700-22-9
Price: $30/20mg
Geissoschizine methyl ether

Catalog No: CFN89459
CAS No: 60314-89-8
Price: $268/10mg
Deoxypodophyllotoxin

Catalog No: CFN99888
CAS No: 19186-35-7
Price: $268/10mg
Pimaric acid

Catalog No: CFN99382
CAS No: 127-27-5
Price: $ /
Glycitin

Catalog No: CFN99105
CAS No: 40246-10-4
Price: $70/20mg
Isovitexin 2''-O-arabinoside

Catalog No: CFN90943
CAS No: 53382-71-1
Price: $318/10mg
Brazilin

Catalog No: CFN98711
CAS No: 474-07-7
Price: $118/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ursolic acid, a naturally occurring triterpenoid, induces the apoptosis of human cancer cells through multiple signaling pathways. Ursonic acid has antiviral activity against Herpes simplex virus types I and II in vitro; it also could be used in preparation of depression treatment medicine.
Targets: HIV
In vitro:
Bioinformation. 2014 Feb 19;10(2):52-5.
Virtual Screening of Indonesian Herbal Database as HIV-1 Protease Inhibitor.[Pubmed: 24616554]
HIV-1 (Human immunodeficiency virus type 1)׳s infection is considered as one of most harmful disease known by human, the survivability rate of the host reduced significantly when it developed into AIDS. HIV drug resistance is one of the main problems of its treatment and several drug designs have been done to find new leads compound as the cure.
METHODS AND RESULTS:
In this study, in silico virtual screening approach was used to find lead molecules from the library or database of natural compounds as HIV-1 protease inhibitor. Virtual screening against Indonesian Herbal Database with AutoDock was performed on HIV-1 protease.
CONCLUSIONS:
From the virtual screening, top ten compounds obtained were 8-Hydroxyapigenin 8-(2",4"-disulfatoglucuronide), Isoscutellarein 4'-methyl ether, Amaranthin, Torvanol A, Ursonic acid, 5-Carboxypyranocyanidin 3-O-(6"-O-malonyl-beta-glucopyranoside), Oleoside, Jacoumaric acid, Platanic acid and 5-Carboxypyranocyanidin 3-O-beta-glucopyranoside.
Ursonic acid Description
Source: The dried fruit of Ziziphus jujuba.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
3beta-(alpha-L-Arabinopyranosyloxy...

Catalog No: CFN95459
CAS No: 435269-07-1
Price: $318/20mg
5,6,7,3',4',5'-Hexamethoxyflavanon...

Catalog No: CFN95376
CAS No: 74064-17-8
Price: $318/10mg
Cannabisin M

Catalog No: CFN95436
CAS No: 1831134-13-4
Price: $318/5mg
Ephedrannin A

Catalog No: CFN95579
CAS No: 82001-39-6
Price: $318/5mg
Lariciresinol 4'-O-glucoside

Catalog No: CFN95400
CAS No: 107110-16-7
Price: $318/5mg
1,7-Diphenyl-5-hydroxy-4,6-hepten-...

Catalog No: CFN95171
CAS No: 87095-77-0
Price: $318/10mg
Kihadanin D

Catalog No: CFN95482
CAS No: 2770024-83-2
Price: $413/5mg
Clemastanin B

Catalog No: CFN95064
CAS No: 112747-98-5
Price: $368/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1993 mL 10.9963 mL 21.9925 mL 43.985 mL 54.9813 mL
5 mM 0.4399 mL 2.1993 mL 4.3985 mL 8.797 mL 10.9963 mL
10 mM 0.2199 mL 1.0996 mL 2.1993 mL 4.3985 mL 5.4981 mL
50 mM 0.044 mL 0.2199 mL 0.4399 mL 0.8797 mL 1.0996 mL
100 mM 0.022 mL 0.11 mL 0.2199 mL 0.4399 mL 0.5498 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Cell Research:
Phytochemistry. 2005 Feb;66(4):495-501.
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa.[Pubmed: 15694457 ]
Six triterpenes, 3beta-acetoxy-12,19-dioxo-13(18)-oleanene (1), 3beta-acetoxy-19(29)-taraxasten-20alpha-ol (2), 3beta-acetoxy-21alpha,22alpha-epoxytaraxastan-20alpha-ol (3), 3,22-dioxo-20-taraxastene (4), 3beta-acetoxy-11alpha,12alpha-epoxy-16-oxo-14-taraxerene (5), 3beta-acetoxy-25-methoxylanosta-8,23-diene (6) along with nine known triterpenes, 3beta-acetoxy-11alpha,12alpha-epoxy-14-taraxerene (7), 3beta-acetoxy-25-hydroxylanosta-8,23-diene (8), oleanonic acid (9), acetylbetulinic acid (10), betulonic acid (11), acetylursolic acid (12), Ursonic acid (13), ursolic acid (14), and 3-oxofriedelan-28-oic acid (15) were isolated from the aerial roots of Ficus microcarpa, and their structures elucidated by spectroscopic methods.
METHODS AND RESULTS:
The in vitro cytotoxic efficacy of these triterpenes was investigated using three human cancer cell lines, namely, HONE-1 nasopharyngeal carcinoma, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells.
CONCLUSIONS:
Compound 8 and pentacyclic triterpenes 9-15 possessing a carboxylic acid functionality at C-28 showed significant cytotoxic activities against the aforementioned cell lines and gave IC50 values in the range 4.0-9.4 microM.
Structure Identification:
Nat Prod Res. 2015;29(7):628-32.
Two new labdane diterpenoids from the rhizomes of Isodon yuennanensis.[Pubmed: 25420949]

METHODS AND RESULTS:
Two new labdane diterpenoids, s-trans-8(17),12E,14-labdatrien-20-oic acid (1), s-trans-12E,14-labdadien-20,8β-olide (2), along with 10 known compounds, hinokiol (3), Ursonic acid (4), 2α,3α-dihydroxyolean-12-en-28-oic acid (5), 2α,3β,23-trihydroxyolean-12-en-28-oic acid (6), ethyl 3-(3,4-dihydroxyphenyl)lactate (7), ethyl rosmarinate (8), (Z,E)-2-(3,4-dihydroxyphenyl)ethenyl caffeic ester (9), tridecanoic acid (10), β-sitosterol (11) and daucosterol (12), were isolated from the 70% acetone extract of the rhizomes of Isodon yuennanensis.
CONCLUSIONS:
Their structures were elucidated based on the analyses of extensive spectroscopic data and physicochemical properties.
Angelicin

Catalog No: CFN98854
CAS No: 523-50-2
Price: $30/20mg
DL-Syringaresinol

Catalog No: CFN99276
CAS No: 1177-14-6
Price: $ /
Glycyrin

Catalog No: CFN89404
CAS No: 66056-18-6
Price: $368/5mg
Oxyresveratrol

Catalog No: CFN98368
CAS No: 29700-22-9
Price: $30/20mg
Geissoschizine methyl ether

Catalog No: CFN89459
CAS No: 60314-89-8
Price: $268/10mg
Deoxypodophyllotoxin

Catalog No: CFN99888
CAS No: 19186-35-7
Price: $268/10mg
Pimaric acid

Catalog No: CFN99382
CAS No: 127-27-5
Price: $ /
Glycitin

Catalog No: CFN99105
CAS No: 40246-10-4
Price: $70/20mg
Isovitexin 2''-O-arabinoside

Catalog No: CFN90943
CAS No: 53382-71-1
Price: $318/10mg
Brazilin

Catalog No: CFN98711
CAS No: 474-07-7
Price: $118/20mg
Tags: buy Ursonic acid | Ursonic acid supplier | purchase Ursonic acid | Ursonic acid cost | Ursonic acid manufacturer | order Ursonic acid | Ursonic acid distributor