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Vineridine
Vineridine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Vineridine
Price:
CAS No.: 3489-06-3
Catalog No.: CFN98460
Molecular Formula: C22H26N2O5
Molecular Weight: 398.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Vinca erecta
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: Standard reference
Vineridine Description
Source: The herbs of Vinca erecta
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5094 mL 12.5471 mL 25.0941 mL 50.1882 mL 62.7353 mL
5 mM 0.5019 mL 2.5094 mL 5.0188 mL 10.0376 mL 12.5471 mL
10 mM 0.2509 mL 1.2547 mL 2.5094 mL 5.0188 mL 6.2735 mL
50 mM 0.0502 mL 0.2509 mL 0.5019 mL 1.0038 mL 1.2547 mL
100 mM 0.0251 mL 0.1255 mL 0.2509 mL 0.5019 mL 0.6274 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemistry of Natural Compounds,1974,10(4): 496-503.
Absolute configuration of vinerine and vineridine[Reference: WebLink]

METHODS AND RESULTS:
On the basis of an analysis of the circular dichroism and NMR spectra the absolute configuration 7R, 3R, 4S, 15S, 19S, 20S has been established for vinerine; 7S, 3R, 4S, 15S, 19S, 20S for Vineridine; and 7S, 3S, 4R, 15S, 19S, 20S for N-acetylvinerine.
Khimiya Prirodnykh Soedinenii,1966,2(4): 260–265.
The structure of vinerine and vineridine[Reference: WebLink]

METHODS AND RESULTS:
1. The epigeal part ofV. erecta gathered in the Tashkent Oblast in the early vegetation period contains a mixture of alkaloids (2.7%). Separation of the total alkaloids gave vincanine, vincanidine, vinervine, akuammine, kopsinine, pseudokopsinine, and the new bases vinerine and Vineridine. 2. The structure of vinerine has been established by a study of the IR, NMR, and mass spectra.
CONCLUSIONS:
Vineridine is isomeric with vinerine at C3 and C7. 3. A new base, hydroxyindole reserpinine, has been obtained from reserpinine.
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