Structure Identification: |
Chemical & pharmaceutical bulletin, 1984, 32(11), 4702-5. | New quassinoid glycosides, yadanziosides A-H, from Brucea javanica.[Reference: WebLink] | Eight new antileukemic quassinoid glycosides, Yadanzioside A, yadanzioside B, yadanzioside C, yadanzioside D, yadanzioside E, Yadanzioside F, yadanzioside G, and yadanzioside H(1-8) were isolated from seeds of Brucea javanica and their structures were determined by chemical transformation and spectral analysis. | Bull. Chem. Soc. Jpn.,1985, 58(9), 2680-6. | Structures of new quassinoid glycosides, yadanziosides A,B,C,D,E,G,H, and new quassinoids, dehydrobrusatol and dehydrobruceantinol from Brucea javanica (L.) Merr.[Reference: WebLink] | METHODS AND RESULTS:
Quassinoid glycosides, Yadanzioside A, yadanzioside B, yadanzioside C, yadanzioside D, yadanzioside E, yadanzioside G, and yadanzioside H, and two quassinoids, dehydrobrusatol and dehydrobruceantinol were isolated from seeds of Brucea javanica, and their structures were determined.
CONCLUSIONS:
These glycosides showed bitter taste and were demonstrated to have antileukemic activity. |
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