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Natural Products
Catalog No. Information
CFN95449 Senkyunolide N

Senkyunolide N exhibits prostaglandin H endoperoxide synthase-I (COX-I) and endoperoxide synthase-II (COX-II)) Inhibitory activity at pH 7 and at a concentration of 250 pg ml(-1) . Senkyunolide N exhibits topoisomerase-I and -II enzyme inhibitory activity at concentrations of 100, 200 and 200 microg ml(-1). Senkyolide N has insecticidal effect.
CFN99597 Sennidin A

Sennidin A, has two hydroxyanthraquinone-like moieties, exerts inhibition on NS3 helicase with IC50 values of 0.8 uM. Sennidin A in combination with necrosis inducing drugs/therapies may generate synergetic tumoricidal effects on solid malignancies by means of primary debulking and secondary cleansing process. It stimulates glucose incorporation in the phosphatidylinositol 3-kinase (PI3K)- and Akt-dependent in rat adipocytes, but in the IR/IRS1-independent manner.
CFN99903 Sennoside A

Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine, it and Sennoside B have protective effects on gastric lesion. Sennoside A also is a new dual HIV-1 inhibitor effective on HIV-1 replication.
CFN99904 Sennoside B

Sennoside B, a major purgative component, has a potential utility in the treatment of proliferative diseases, through inhibiting PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. It and sennoside A also possess significant gastroprotective activities .
CFN99905 Sennoside C

Sennoside C , aloe-emodin anthrone and rhein anthrone which formed mainly by intraluminal bacterial action, synergistically exert their purgative effects on mice.
CFN99906 Sennoside D

Sennoside D is a natural product from Cassia angustifolia.
CFN95642 Sequoiaflavone

CFN99867 Serpentine

Reference standards.
CFN98499 Serpentinine

Serpentinine may have antihypertensive effect.
CFN97034 Sesamin

Sesamin has antifibrotic, cholesterol-lowering, anti-cancer, antioxidative, neuroprotective, anti-atherosclerosis, anti-inflammatory properties, it also might be beneficial in the prevention of hypertension and stroke. Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-α-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.Sesamin also can protect β-cells from damage caused by AGEs through suppressing NADPH oxidase-mediated oxidative stress.