ChemFaces have 21 compounds are similar structure. 4'-Methoxychalcone (CAS#959-23-9); 4,4'-Dimethoxychalcone (CAS#2373-89-9); Isoliquiritigenin (CAS#961-29-5); 2'-O-Methylisoliquiritigenin (CAS#51828-10-5); 3-Deoxysappanchalcone (CAS#112408-67-0); 4,2'-Dihydroxy-4'-methoxychalcone (CAS#63529-06-6); Phloretin (CAS#60-82-2); Asebogenin (CAS#520-42-3); 2',6'-Dihydroxy 4',4-dimethoxydihydrochalcone (CAS#35241-54-4); 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) (CAS#111316-17-7); Helichrysetin (CAS#62014-87-3); 2,4-Dihydroxy-4,6-dimethoxydihydrochalcone (CAS#75679-58-2); 2',6'-Dihydroxy-4,4'-dimethoxychalcone (CAS#20621-49-2); 4-O-Methylhelichrysetin (CAS#56121-44-9); 2'-O-Methylhelichrysetin (CAS#123316-64-3); Flavokawain C (CAS#56798-34-6); Flavokawain A (CAS#3420-72-2); 2',4',6',4-Tetramethoxychalcone (CAS#94103-36-3); 2',4'-Dihydroxy-2,3',6'-trimethoxychalcone (CAS#100079-39-8); 3'-Methylflavokawin (CAS#1044743-35-2); 3'-Methyl-4-O-methylhelichrysetin (CAS#109471-13-8).
Those compounds are series compounds, which having the similar structure but only some different in the individual atoms, functional groups and substructures. Maybe they also have the different physicochemical property, bioactivity and pharmacological property. In the drug design and reserach, they play an important role of improving the success rate of drug screening, researching of drug toxicity and acquiring of other data.