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4,2'-Dihydroxy-4'-methoxychalcone
4,2'-Dihydroxy-4'-methoxychalcone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4,2'-Dihydroxy-4'-methoxychalcone
Price:
CAS No.: 63529-06-6
Catalog No.: CFN89427
Molecular Formula: C16H14O4
Molecular Weight: 270.28 g/mol
Purity: >=98%
Type of Compound: Chalcones
Physical Desc.: Powder
Source: The resins of Xanthorrhoea hastilis R. BR.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 4,2'-Dihydroxy-4'-methoxychalcone shows allergy-preventive effects.
4,2'-Dihydroxy-4'-methoxychalcone Description
Source: The resins of Xanthorrhoea hastilis R. BR.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.6999 mL 18.4993 mL 36.9987 mL 73.9973 mL 92.4967 mL
5 mM 0.74 mL 3.6999 mL 7.3997 mL 14.7995 mL 18.4993 mL
10 mM 0.37 mL 1.8499 mL 3.6999 mL 7.3997 mL 9.2497 mL
50 mM 0.074 mL 0.37 mL 0.74 mL 1.4799 mL 1.8499 mL
100 mM 0.037 mL 0.185 mL 0.37 mL 0.74 mL 0.925 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2007 Apr;55(4):675-8.
Allergy-preventive flavonoids from Xanthorrhoea hastilis.[Pubmed: 17409571]
Allergy-preventive activity was demonstrated for an extract of resins from Xanthorrhoea hastilis R. BR. in a search for allergy-preventive substances from natural sources.
METHODS AND RESULTS:
By bioassay-directed fractionation of this plant extract, a new flavanone, 3',5'-dihydroxy-7,4'-dimethoxyflavanone (1), and two new chalcones, 3,5,2'-trihydroxy-4,4'-dimethoxychalcone (2) and 5,2'-dihydroxy-3,4,4'-trimethoxychalcone (3), were isolated together with five known compounds, 5'-hydroxy-7,3',4'-trimethoxyflavanone (4), 3'-hydroxy-7,4'-dimethoxyflavanone (5), liquiritigenin 7-methyl ether (6), 4,2'-Dihydroxy-4'-methoxychalcone (7) and sakuranetin (8).
CONCLUSIONS:
The structures of 1, 2 and 3 were elucidated by spectroscopic methods. All of these compounds showed allergy-preventive effects.
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CAS No: 112-80-1
Price: $30/20mg
6-Prenylnaringenin

Catalog No: CFN92017
CAS No: 68236-13-5
Price: $268/10 mg
Scutellarin

Catalog No: CFN99112
CAS No: 27740-01-8
Price: $30/20mg
Damulin B

Catalog No: CFN91837
CAS No: 1202868-75-4
Price: $288/5mg
Abietic acid

Catalog No: CFN90587
CAS No: 514-10-3
Price: $40/20mg
Nonivamide

Catalog No: CFN90179
CAS No: 2444-46-4
Price: $30/20mg
Sennoside B

Catalog No: CFN99904
CAS No: 128-57-4
Price: $40/20mg
Cryptochlorogenic acid

Catalog No: CFN99117
CAS No: 905-99-7
Price: $90/20mg
Sarsasapogenin

Catalog No: CFN99779
CAS No: 126-19-2
Price: $40/20mg
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