Science | Nature | Cell | View More
Natural Products
1,5,6-Trihydroxyxanthone
1,5,6-Trihydroxyxanthone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1,5,6-Trihydroxyxanthone
Price:
CAS No.: 5042-03-5
Catalog No.: CFN89364
Molecular Formula: C13H8O5
Molecular Weight: 244.19 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The woods of Garcinia succifolia Kurz.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Pretoria (South Africa)
  • Mahatma Gandhi University (India)
  • Universidad Veracuzana (Mexico)
  • Universiti Malaysia Pahang (Malaysia)
  • Institute of Tropical Disease U... (Indonesia)
  • University of Hawaii Cancer Center (USA)
  • University of Indonesia (Indonesia)
  • University of Virginia (USA)
  • Seoul National University of Sc... (Korea)
  • Gyeongsang National University (Korea)
  • University of Vienna (Austria)
  • More...
Package
Featured Products
Pulegone

Catalog No: CFN93286
CAS No: 89-82-7
Price: $30/20mg
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Alisol A 24-acetate

Catalog No: CFN90198
CAS No: 18674-16-3
Price: $118/20mg
Ginsenoside F5

Catalog No: CFN95034
CAS No: 189513-26-6
Price: $298/20mg
Lycorine

Catalog No: CFN90263
CAS No: 476-28-8
Price: $30/20mg
Tanshinone I

Catalog No: CFN98953
CAS No: 568-73-0
Price: $30/20mg
Isobutylshikonin

Catalog No: CFN92023
CAS No: 52438-12-7
Price: $268/10mg
5-O-Feruloylquinic acid

Catalog No: CFN92889
CAS No: 40242-06-6
Price: $318/10mg
Phytol

Catalog No: CFN99630
CAS No: 150-86-7
Price: $30/20mg
Chrysin

Catalog No: CFN98741
CAS No: 480-40-0
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 1,5,6-Trihydroxyxanthone exhibits antibacterial activity against Gram-positive bacteria.
Targets: EGFR | Antifection
In vitro:
Molecules. 2014 Nov 28;19(12):19923-34.
Antibacterial and EGFR-tyrosine kinase inhibitory activities of polyhydroxylated xanthones from Garcinia succifolia.[Pubmed: 25460314 ]
Chemical investigation of the methanol extract of the wood of Garcinia succifolia Kurz (Clusiaceae) led to the isolation of 1,5-dihydroxyxanthone (1), 1,7-dihydroxyxanthone (2), 1,3,7-trihydroxyxanthone (3), 1,5,6-Trihydroxyxanthone (4), 1,6,7-trihydroxyxanthone (5), and 1,3,6,7-tetrahydroxyxanthone (6).
METHODS AND RESULTS:
All of the isolated xanthones were evaluated for their antibacterial activity against bacterial reference strains, two Gram-positive (Staphylococcus aureus ATTC 25923, Bacillus subtillis ATCC 6633) and two Gram-negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853), and environmental drug-resistant isolates (S. aureus B1, Enteroccoccus faecalis W1, and E. coli G1), as well as for their epidermal growth factor receptor (EGFR) of tyrosine kinase inhibitory activity.
CONCLUSIONS:
Only 1,5,6-trihydroxy-(4), 1,6,7-trihydroxy-(5), and 1,3,6,7-tetrahydroxyxanthones (6) exhibited antibacterial activity against Gram-positive bacteria, however none was active against vancomycin-resistant E. faecalis. Additionally, 1,7-dihydroxyxanthone (2) showed synergism with oxacillin, but not with ampicillin. On the other hand, only 1,5-dihydroxyxanthone (1) and 1,7-dihydroxyxanthone (2) were found to exhibit the EGFR-tyrosine kinase inhibitory activity, with IC50 values of 90.34 and 223 nM, respectively.
1,5,6-Trihydroxyxanthone Description
Source: The woods of Garcinia succifolia Kurz.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
11alpha-hydroxy-3,7-dioxo-5alpha-l...

Catalog No: CFN95592
CAS No: 1245703-70-1
Price: $413/5mg
15-Methoxy-16-oxo-15,16H-strictic ...

Catalog No: CFN95261
CAS No: 1356388-38-9
Price: $368/5mg
8-Hydroxypinoresinol diglucoside

Catalog No: CFN95083
CAS No: 112747-99-6
Price: $318/5mg
Rhamnocitrin 3-apiosyl-(1->2)-gluc...

Catalog No: CFN95145
CAS No: 148031-68-9
Price: $318/10mg
New compound 2

Catalog No: CFN95181
CAS No: N/A
Price: $318/5mg
Andrographidine A

Catalog No: CFN95210
CAS No: 113963-37-4
Price: $318/10mg
Peltatoside 7-O-beta-glucopyranosi...

Catalog No: CFN95565
CAS No: 813466-12-5
Price: $318/20mg
Benzylpropyl acetate

Catalog No: CFN95495
CAS No: 7492-40-2
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0952 mL 20.4759 mL 40.9517 mL 81.9034 mL 102.3793 mL
5 mM 0.819 mL 4.0952 mL 8.1903 mL 16.3807 mL 20.4759 mL
10 mM 0.4095 mL 2.0476 mL 4.0952 mL 8.1903 mL 10.2379 mL
50 mM 0.0819 mL 0.4095 mL 0.819 mL 1.6381 mL 2.0476 mL
100 mM 0.041 mL 0.2048 mL 0.4095 mL 0.819 mL 1.0238 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Pulegone

Catalog No: CFN93286
CAS No: 89-82-7
Price: $30/20mg
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Alisol A 24-acetate

Catalog No: CFN90198
CAS No: 18674-16-3
Price: $118/20mg
Ginsenoside F5

Catalog No: CFN95034
CAS No: 189513-26-6
Price: $298/20mg
Lycorine

Catalog No: CFN90263
CAS No: 476-28-8
Price: $30/20mg
Tanshinone I

Catalog No: CFN98953
CAS No: 568-73-0
Price: $30/20mg
Isobutylshikonin

Catalog No: CFN92023
CAS No: 52438-12-7
Price: $268/10mg
5-O-Feruloylquinic acid

Catalog No: CFN92889
CAS No: 40242-06-6
Price: $318/10mg
Phytol

Catalog No: CFN99630
CAS No: 150-86-7
Price: $30/20mg
Chrysin

Catalog No: CFN98741
CAS No: 480-40-0
Price: $40/20mg
Tags: buy 1,5,6-Trihydroxyxanthone | 1,5,6-Trihydroxyxanthone supplier | purchase 1,5,6-Trihydroxyxanthone | 1,5,6-Trihydroxyxanthone cost | 1,5,6-Trihydroxyxanthone manufacturer | order 1,5,6-Trihydroxyxanthone | 1,5,6-Trihydroxyxanthone distributor