2'-O-Methylperlatolic acid | CAS:38968-07-9

2'-O-Methylperlatolic acid

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Description:

2'-O-Methylperlatolic acid and confluentic acid are monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.

Targets:

MAO

In vitro:

Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1198-201.

Confluentic acid and 2'-O-methylperlatolic acid, monoamine oxidase B inhibitors in a Brazilian plant, Himatanthus sucuuba.[Pubmed: 8069971]

METHODS AND RESULTS:
Monoamine oxidase B (MAO-B) inhibitors were isolated from the bark of a Brazilian plant, Himatanthus sucuuba (SPR.). Assignments of the 1H- and 13C-NMR data using two dimensional (2D)-NMR techniques showed the active components to be known lichen depsides, confluentic acid (1) and 2'-O-Methylperlatolic acid (2).
CONCLUSIONS:
The depside (1) showed selective inhibition of MAO-B with IC50 value of 0.22 microM.

2'-O-Methylperlatolic acid Description

Source:	The herbs of Illicium merrillianum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	2'-O-Methylperlatolic acid
Price:
CAS No.:	38968-07-9
Catalog No.:	CFN98621
Molecular Formula:	C₂₆H₃₄O₇
Molecular Weight:	458.6 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Illicium merrillianum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Phenols Compound Library MAO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1805 mL	10.9027 mL	21.8055 mL	43.611 mL	54.5137 mL
5 mM	0.4361 mL	2.1805 mL	4.3611 mL	8.7222 mL	10.9027 mL
10 mM	0.2181 mL	1.0903 mL	2.1805 mL	4.3611 mL	5.4514 mL
50 mM	0.0436 mL	0.2181 mL	0.4361 mL	0.8722 mL	1.0903 mL
100 mM	0.0218 mL	0.109 mL	0.2181 mL	0.4361 mL	0.5451 mL

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