Structure Identification: |
Journal of Tropical and Subtropical Botany, 2015,23(6) :703-709. | Qualitative and Quantitative Analysis of Diterpenoid Compounds in Sphagneticola trilobata (L.) Pruski[Reference: WebLink] | In order to understand the chemical constituents of Sphagneticola trilobata (L.) Pruski, eight diterpenoids were isolated from the ethanol extract of its whole plants.
METHODS AND RESULTS:
On the basis of spectral data, they were identiifed as ent-16β,17-dihydroxy-9(11)-kauren-19-oic acid (1), cussovantonin B (2), ent-16-kauren-19-oic acid (3), ent-3β-hydroxy-16-kauren-19-oic acid (4), 16α-hydroxy-ent-kauran-19-oic acid (5), 2β,16α-dihydroxy-ent-kauran-19-oic acid (6), 3alpha-Angeloyloxypterokaurene L3 (7) and pterokaurene L3 (8). Compound 4 were isolated from genus Sphagneticola for the first time, and compounds 1, 2 and 6 were isolated from S. trilobata for the first time. Compound 3 showed strong antibacterial activity against several bacteria and further inhibited signiifcantlyα-glucosidase activity in vitro.
CONCLUSIONS:
Based on structural derivation with pentalfuorobenzyl bromide coupled with GC-MS techniques, the contents of compound 3 in the stem and leaves of S. trilobata were (1.00±0.21) mg g–1 FW and (0.78±0.04) mg g–1 FW, respectively. |
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