6-Hydroxybenzofuran-2(3H)-one | CAS:2688-49-5

6-Hydroxybenzofuran-2(3H)-one

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6-Hydroxybenzofuran-2(3H)-one Description

Source:	The herbs of Flueggea acicularis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Letters in Drug Design & Discovery, 2013,10(9):798-807.

Synthesis, Antimicrobial Activities and Molecular Docking Studies of Novel 6-Hydroxybenzofuran-3(2H)-one Based 2,4-Disubstituted 1,3-Thiazoles.[Reference: WebLink]

METHODS AND RESULTS:
Synthesis, characterization and investigation of antibacterial and antifungal activities of thirteen novel 6-Hydroxybenzofuran-2(3H)-one(6-hydroxybenzofuran-3(2H)-one) based 2,4-disubstituted 1,3-thiazoles are presented. Their structures were determined using NMR, FAB MS and HRMS analyses. The results of microbiological screening reveal that three derivatives containing fluorine, bromine and hydrogen substituents at the phenyl ring are the most active antimicrobial compounds.
CONCLUSIONS:
Molecular docking studies of all compounds on the active sites of microbial enzymes indicated a possible target N-myristoyltransferase (NMT).

Product Name	6-Hydroxybenzofuran-2(3H)-one
Price:
CAS No.:	2688-49-5
Catalog No.:	CFN98320
Molecular Formula:	C₈H₆O₃
Molecular Weight:	150.1 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Flueggea acicularis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library Antifection Inhibitor Library

Description:	Molecular docking studies of all compounds( thirteen novel 6-Hydroxybenzofuran-2(3H)-one(6-hydroxybenzofuran-3(2H)-one)) on the active sites of microbial enzymes indicated a possible target N-myristoyltransferase (NMT).
Targets:	Antifection

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.6622 mL	33.3111 mL	66.6223 mL	133.2445 mL	166.5556 mL
5 mM	1.3324 mL	6.6622 mL	13.3245 mL	26.6489 mL	33.3111 mL
10 mM	0.6662 mL	3.3311 mL	6.6622 mL	13.3245 mL	16.6556 mL
50 mM	0.1332 mL	0.6662 mL	1.3324 mL	2.6649 mL	3.3311 mL
100 mM	0.0666 mL	0.3331 mL	0.6662 mL	1.3324 mL	1.6656 mL

CFN96090	2',4',6'-Trihydroxyacetophenone	480-66-0	168.2	C₈H₈O₄
CFN97051	2,4-Dihydroxyphenylacetic acid	614-82-4	168.2	C₈H₈O₄
CFN91665	Phaseoloidin	118555-82-1	330.29	C₁₄H₁₈O₉
CFN70282	Primverin	154-60-9	476.4	C₂₀H₂₈O₁₃
CFN70283	Primulaverin	154-61-0	476.4	C₂₀H₂₈O₁₃
CFN97158	Ethyl 2,4-dihydroxyphenylacetate	67828-62-0	196.2	C₁₀H₁₂O₄
CFN93816	Homogentisic acid	451-13-8	168.2	C₈H₈O₄
CFN98320	6-Hydroxybenzofuran-2(3H)-one	2688-49-5	150.1	C₈H₆O₃
CFN97121	Benzoic acid	65-85-0	122.1	C₇H₆O₂
CFN96014	3-Methylcatechol	488-17-5	124.1	C₇H₈O₂