Baccatin VIII | CAS:1623410-10-5 | Manufacturer ChemFaces

Baccatin VIII

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Baccatin VIII exhibits inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 uM, respectively.

In vitro:

Nat Prod Bioprospect. 2014 Feb;4(1):47-51

New Taxane Diterpenoids from Taxus yunnanensis.[Pubmed: 24660136 ]

METHODS AND RESULTS:
Three hitherto unknown taxane diterpenoids, namely Baccatin VIII (1), baccatin IX (2), and baccatin X (3), along with 10 known analogues were isolated from an ethanolic extract of the twigs and leaves of Taxus yunnanensis. The new structures were characterized based on extensive spectroscopic analysis.
CONCLUSIONS:
Compounds 1 and 2 were tested for their in vitro cytotoxicity against five human tumor cell lines, and 1 exhibited inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 μM, respectively.

Baccatin VIII Description

Source:	The twigs and leaves of Taxus yunnanensis.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Baccatin VIII
Price:
CAS No.:	1623410-10-5
Catalog No.:	CFN96907
Molecular Formula:	C₃₃H₄₂O₁₃
Molecular Weight:	646.68 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The twigs and leaves of Taxus yunnanensis.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.5464 mL	7.7318 mL	15.4636 mL	30.9272 mL	38.659 mL
5 mM	0.3093 mL	1.5464 mL	3.0927 mL	6.1854 mL	7.7318 mL
10 mM	0.1546 mL	0.7732 mL	1.5464 mL	3.0927 mL	3.8659 mL
50 mM	0.0309 mL	0.1546 mL	0.3093 mL	0.6185 mL	0.7732 mL
100 mM	0.0155 mL	0.0773 mL	0.1546 mL	0.3093 mL	0.3866 mL

CFN98331	Baccatin III	27548-93-2	586.6	C₃₁H₃₈O₁₁
CFN97267	19-Hydroxybaccatin III	78432-78-7	602.6	C₃₁H₃₈O₁₂
CFN89390	7-Xylosyl-10-deacetylbaccatin III	157664-03-4	676.70	C₃₄H₄₄O₁₄
CFN96908	Baccatin IX	1623410-12-7	604.64	C₃₁H₄₀O₁₂
CFN96909	Baccatin X	1623069-76-0	604.64	C₃₁H₄₀O₁₂
CFN97197	14beta-Benzoyloxy-2-deacetylbaccatin VI	705973-69-9	730.8	C₃₇H₄₆O₁₅
CFN89062	9-Dihydro-13-acetylbaccatin III	142203-65-4	630.68	C₃₃H₄₂O₁₂
CFN96925	Baccatin VI	57672-79-4	714.76	C₃₇H₄₆O₁₄
CFN96907	Baccatin VIII	1623410-10-5	646.68	C₃₃H₄₂O₁₃
CFN98976	Baccatin IV	57672-77-2	652.7	C₃₂H₄₄O₁₄