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Beta-Aflatrem
Beta-Aflatrem
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Beta-Aflatrem
Price:
CAS No.: 144446-23-1
Catalog No.: CFN96409
Molecular Formula: C32H39NO4
Molecular Weight: 501.66 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: From Aspergillus flavus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Mar Drugs. 2014 Jun 30;12(7):3970-81.
Indole diterpenoids and isocoumarin from the fungus, Aspergillus flavus, isolated from the prawn, Penaeus vannamei.[Pubmed: 24983640 ]

METHODS AND RESULTS:
Two new indole-diterpenoids (1 and 2) and a new isocoumarin (3), along with the known β-aflatrem (Beta-Aflatrem,4), paspalinine (5), leporin B (6), α-cyclopiazonic acid (7), iso-α-cyclopiazonic acid (8), ditryptophenaline (9), aflatoxin B1 (10), 7-O-acetylkojic acid (11) and kojic acid (12), were isolated from the fermentation broth of the marine-derived fungus, Aspergillus flavus OUCMDZ-2205. The structures of Compounds 1-12 were elucidated by spectroscopic analyses, quantum ECD calculations and the chemical method.
CONCLUSIONS:
New Compound 1 exhibited antibacterial activity against Staphylococcus aureus with a MIC value of 20.5 μM. Both new Compounds 1 and 2 could arrest the A549 cell cycle in the S phase at a concentration of 10 μM. Compound 1 showed PKC-beta inhibition with an IC50 value of 15.6 μM. In addition, the absolute configurations of the known compounds, 4-6 and leporin A (6a), were also determined for the first time.
Beta-Aflatrem Description
Source: From Aspergillus flavus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

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PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9934 mL 9.9669 mL 19.9338 mL 39.8676 mL 49.8345 mL
5 mM 0.3987 mL 1.9934 mL 3.9868 mL 7.9735 mL 9.9669 mL
10 mM 0.1993 mL 0.9967 mL 1.9934 mL 3.9868 mL 4.9835 mL
50 mM 0.0399 mL 0.1993 mL 0.3987 mL 0.7974 mL 0.9967 mL
100 mM 0.0199 mL 0.0997 mL 0.1993 mL 0.3987 mL 0.4983 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Rhynchophylline

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CAS No: 76-66-4
Price: $98/20mg
Nodakenin

Catalog No: CFN90232
CAS No: 495-31-8
Price: $70/20mg
Tamarixetin

Catalog No: CFN97027
CAS No: 603-61-2
Price: $ /
Physalin A

Catalog No: CFN92940
CAS No: 23027-91-0
Price: $318/5 mg
Pyrogallol

Catalog No: CFN97443
CAS No: 87-66-1
Price: $30/20mg
Vicenin -1

Catalog No: CFN92030
CAS No: 35927-38-9
Price: $318/20mg
Alpinumisoflavone

Catalog No: CFN98440
CAS No: 34086-50-5
Price: $ /
Trilobatin

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Price: $30/20mg
Betaine

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Ginsenoside Rg3

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Price: $40/20mg
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