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Carmichaenine A
Carmichaenine A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Carmichaenine A
Price:
CAS No.: 2065228-59-1
Catalog No.: CFN89452
Molecular Formula: C31H43NO7
Molecular Weight: 541.67 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The aerial parts of Aconitum carmichaeli.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Biological Activity
Description: Carmichaenine A is a natiral product from Aconitum carmichaeli.
Carmichaenine A Description
Source: The aerial parts of Aconitum carmichaeli.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8461 mL 9.2307 mL 18.4614 mL 36.9228 mL 46.1536 mL
5 mM 0.3692 mL 1.8461 mL 3.6923 mL 7.3846 mL 9.2307 mL
10 mM 0.1846 mL 0.9231 mL 1.8461 mL 3.6923 mL 4.6154 mL
50 mM 0.0369 mL 0.1846 mL 0.3692 mL 0.7385 mL 0.9231 mL
100 mM 0.0185 mL 0.0923 mL 0.1846 mL 0.3692 mL 0.4615 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry Letters, 2015,13:390-393.
Five new C19-diterpenoid alkaloids from Aconitum carmichaeli.[Reference: WebLink]

METHODS AND RESULTS:
Five new aconitine-type C19-diterpenoid alkaloids, namely, Carmichaenine A, carmichaenine B, carmichaenine C, carmichaenine D, carmichaenine E(1–5), and six known diterpenoid alkaloids, namely, 14-benzoylneoline (6), neoline (7), 10-hydroxyneoline (8), neolinine (9), songoramine (10), and songorine (11), were isolated from the aerial parts of Aconitum carmichaeli.
CONCLUSIONS:
Their structures were determined by extensive spectroscopic methods, especially 2D NMR analyses. Compounds 8 and 9 were isolated for the first time from A. carmichaeli.
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