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Cerberic acid
Cerberic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Cerberic acid
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CAS No.: 65597-44-6
Catalog No.: CFN97120
Molecular Formula: C11H8O5
Molecular Weight: 220.2 g/mol
Purity: >=98%
Type of Compound: Iridoids
Physical Desc.: Yellow powder
Source: The herbs of Cerbera manghas L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Cerberic acids A possesses weak cytotoxic activity against HepG2, MCF-7, and HeLa cell lines with IC(50) values of 44.7, 52.3, 48.7 ug/ml, respectively.
In vitro:
Fitoterapia. 2010 Oct;81(7):852-4.
Phenylpropionic acid derivates from the bark of Cerbera manghas.[Pubmed: 20546844 ]

METHODS AND RESULTS:
Two new phenylpropionic acid derivates, Cerberic acid A (1) and Cerberic acid B (2), were isolated from the bark of Cerbera manghas. Their structures were established on the basis of spectroscopic methods including IR, ESI-FT-ICR-MS, 1D and 2D NMR.
CONCLUSIONS:
Primary bioassays showed that compound 1 possessed weak cytotoxic activity against HepG2, MCF-7, and HeLa cell lines with IC(50) values of 44.7, 52.3, 48.7 μg/ml, respectively.
Cerberic acid Description
Source: The herbs of Cerbera manghas L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5413 mL 22.7066 mL 45.4133 mL 90.8265 mL 113.5332 mL
5 mM 0.9083 mL 4.5413 mL 9.0827 mL 18.1653 mL 22.7066 mL
10 mM 0.4541 mL 2.2707 mL 4.5413 mL 9.0827 mL 11.3533 mL
50 mM 0.0908 mL 0.4541 mL 0.9083 mL 1.8165 mL 2.2707 mL
100 mM 0.0454 mL 0.2271 mL 0.4541 mL 0.9083 mL 1.1353 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97119Cerbinal65597-42-4204.2 C11H8O4
CFN97120Cerberic acid65597-44-6220.2 C11H8O5
CFN95668Jatairidoid A1393577-29-1384.4C19H28O8
CFN95669Jatairidoid B1393577-30-4384.4C19H28O8
CFN95670Jatamanvaltrate N1395056-08-2384.4C19H28O8
CFN90205Valepotriate18296-44-1422.47C22H30NO8
CFN96822Didrovaltrate18296-45-2424.49C22H32O8
CFN96823IVHD-valtrate28325-56-6540.60C27H40O11
CFN96825Acevaltrate25161-41-5480.51C24H32O10
CFN96457Valerosidate29505-31-5462.49C21H34O11
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