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Coulteropine
Coulteropine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Coulteropine
Price:
CAS No.: 6014-62-6
Catalog No.: CFN89127
Molecular Formula: C21H21NO6
Molecular Weight: 383.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The aerial parts of Papaver rhoeas L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Coulteropine is a natural product from Papaver rhoeas L.
Coulteropine Description
Source: The aerial parts of Papaver rhoeas L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6082 mL 13.0412 mL 26.0824 mL 52.1648 mL 65.2061 mL
5 mM 0.5216 mL 2.6082 mL 5.2165 mL 10.433 mL 13.0412 mL
10 mM 0.2608 mL 1.3041 mL 2.6082 mL 5.2165 mL 6.5206 mL
50 mM 0.0522 mL 0.2608 mL 0.5216 mL 1.0433 mL 1.3041 mL
100 mM 0.0261 mL 0.1304 mL 0.2608 mL 0.5216 mL 0.6521 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Pharm Biol. 2017 Dec;55(1):1894-1898.
Variation of alkaloid contents and antimicrobial activities of Papaver rhoeas L. growing in Turkey and northern Cyprus.[Pubmed: 28633584 ]
From the aerial parts of P. rhoeas samples, alkaloids were isolated by column and preparative thin-layer chromatography.
METHODS AND RESULTS:
The alkaloids were identified by comparing their spectral data (UV, IR and 1H-NMR) and TLC Rf values with those of authentic samples. The antimicrobial study was carried out by microbroth dilution technique against six strains of bacteria and three strains of fungi. RESULTS: Twelve different alkaloids belonging to proaporphine (mecambrine), aporphine (roemerine), promorphinan (salutaridine), protopine (Coulteropine and protopine) and rhoeadine (epiglaucamine, glaucamine, glaudine, isorhoeadine, isorhoeagenine, rhoeadine and rhoeagenine) groups were isolated. The most significant activity was observed with the alkaloid extract of P8 against Staphylococcus aureus with a MIC value of 1.22 μg/mL and against Candida albicans with a MIC value of 2.4 μg/mL.
CONCLUSIONS:
The results indicate that P. rhoeas samples (P8 and P9), which contain roemerine as their major alkaloid, were the most active extracts.
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Withaferin A

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CAS No: 5119-48-2
Price: $298/20mg
Sophoraflavanone G

Catalog No: CFN92005
CAS No: 97938-30-2
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Piperlonguminine

Catalog No: CFN91121
CAS No: 5950-12-9
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