Cyclomusalenone | CAS:30452-60-9 | Manufacturer ChemFaces

Cyclomusalenone

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Cyclomusalenone Description

Source:	The herbs of Musa sapientum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Kinase Assay:

Medicinal Chemistry Research. 2015 May;24(5):2177-2182.

Synthesis and evaluation of 29-norcycloartane triterpenoids as α-glucosidase inhibitors.[Reference: WebLink]

METHODS AND RESULTS:
A series of oxygen and nitrogen derivatives of 29-norcycloartane triterpenoids have been synthesized on the basis of Cyclomusalenone isolated from Musa balbisiana Colla. The structures of new compounds have been established by an NMR spectroscopy analysis, and inhibitory activity against α-glucosidase was evaluated.
CONCLUSIONS:
Among tested compounds, 2,3-isoxazoloCyclomusalenone is discovered as a new potent α-glucosidase inhibitor with IC50 value 20.4 μM being 30- and 20-fold more active than initial Cyclomusalenone and marketed drug acarbose.

Structure Identification:

Chemical & pharmaceutical bulletin.1997 Apr15; 45(4):744-746.

4-Epicycloeucalenone and 4-Epicyclomusalenone : Two 3-Oxo-28-norcycloartanes from the Fruit Peel of Musa sapientum L.[Reference: WebLink]

METHODS AND RESULTS:
Two 3-oxo-28-norcycloartane-type triterpenes, 4-epicycloeucalenone and 4-epiCyclomusalenone, and two known 3-oxo-29-norcycloartanes, cycloeucalenone and Cyclomusalenone, were isolated from the n-hexane extract of the fruit peel of Musa sapientum L. (banana). The structures of the 28-norcycloartanes were determined by spectroscopic and chemical methods.

Product Name	Cyclomusalenone
Price:
CAS No.:	30452-60-9
Catalog No.:	CFN97763
Molecular Formula:	C₃₀H₄₈O
Molecular Weight:	424.71 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Musa sapientum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alpha-glucosidase inhibitors Compound Library Triterpenoids Compound Library

Description:	Cyclomusalenone is a potent α-glucosidase inhibitor.
Targets:	α-glucosidase

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3545 mL	11.7727 mL	23.5455 mL	47.091 mL	58.8637 mL
5 mM	0.4709 mL	2.3545 mL	4.7091 mL	9.4182 mL	11.7727 mL
10 mM	0.2355 mL	1.1773 mL	2.3545 mL	4.7091 mL	5.8864 mL
50 mM	0.0471 mL	0.2355 mL	0.4709 mL	0.9418 mL	1.1773 mL
100 mM	0.0235 mL	0.1177 mL	0.2355 mL	0.4709 mL	0.5886 mL

CFN97994	Cycloartanol	4657-58-3	428.7	C₃₀H₅₂O
CFN99496	24-Methylenecycloartan-3-ol	1449-09-8	440.8	C₃₁H₅₂O
CFN99370	24-Methylenecycloartanol acetate	1259-94-5	482.8	C₃₃H₅₄O₂
CFN91778	24-Methylene cycloartanyl ferulate	469-36-3	616.91	C₄₁H₆₀O₄
CFN96941	24-Methylenecycloartanone	1449-08-7	438.74	C₃₁H₅₀O
CFN97878	24-Methylenecycloartane-3beta,26-diol	17020-27-8	456.8	C₃₁H₅₂O₂
CFN98074	23-deoxojessic acid	215609-93-1	486.7	C₃₁H₅₀O₄
CFN99619	1-Dehydroxy-23-deoxojessic acid	149252-87-9	470.7	C₃₁H₅₀O₃
CFN98701	Cycloeucalenol	469-39-6	426.7	C₃₀H₅₀O
CFN97763	Cyclomusalenone	30452-60-9	424.71	C₃₀H₄₈O