Science | Nature | Cell | View More
Natural Products
Erucifoline
Erucifoline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Erucifoline
Price:
CAS No.: 40158-95-0
Catalog No.: CFN00369
Molecular Formula: C18H23NO6
Molecular Weight: 349.38 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Senecio argunensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • The Vancouver Prostate Centre (... (Canada)
  • John Innes Centre (United Kingdom)
  • Korea Food Research Institute(K... (Korea)
  • University of Malaya (Malaysia)
  • Medizinische Universit?t Wien (Austria)
  • University of Dicle (Turkey)
  • University of Virginia (USA)
  • University of Madras (India)
  • Universidade Federal de Pernamb... (Brazil)
  • University of Toronto (Canada)
  • Institute of Chinese Materia Me... (China)
  • More...
Package
Featured Products
Taxifolin

Catalog No: CFN98734
CAS No: 480-18-2
Price: $30/20mg
Scutellarein

Catalog No: CFN98557
CAS No: 529-53-3
Price: $60/20mg
Myricetin 3-O-beta-D-glucopyranoside

Catalog No: CFN80163
CAS No: 19833-12-6
Price: $413/5mg
(-)-Bilobalide

Catalog No: CFN99789
CAS No: 33570-04-6
Price: $40/20mg
Cryptochlorogenic acid

Catalog No: CFN99117
CAS No: 905-99-7
Price: $90/20mg
Notoginsenoside Fe

Catalog No: CFN93282
CAS No: 88105-29-7
Price: $100/20mg
Taraxasterol

Catalog No: CFN99074
CAS No: 1059-14-9
Price: $338/20mg
Umbelliferone

Catalog No: CFN97503
CAS No: 93-35-6
Price: $30/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Taxiphyllin

Catalog No: CFN98070
CAS No: 21401-21-8
Price: $ /
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Erucifoline and Jacobine are feeding deterrents and toxic compounds against insect herbivores.
In vitro:
J Chem Ecol. 2014 Jun;40(6):609-16.
Toxicity of pyrrolizidine alkaloids to Spodoptera exigua using insect cell lines and injection bioassays.[Pubmed: 24981118]

METHODS AND RESULTS:
Pyrrolizidine alkaloids (PAs) are feeding deterrents and toxic compounds to generalist herbivores. Among the PAs of Jacobaea vulgaris Gaertn, jacobine and Erucifoline are the most effective against insect herbivores as indicated by correlative studies. Because little is known about the effect of jacobine and Erucifoline as individual PAs, we isolated these compounds from their respective Jacobaea chemotypes. These PAs and other commercially available senecionine-like PAs, including senecionine, seneciphylline, retrorsine, and senkirkine, were tested as free base and N-oxide forms at a range of 0-70 ppm. Feeding bioassays using live insects are closer to the natural pattern but require relatively large amounts of test compounds. We, therefore, compared the toxicity of PAs using both Spodoptera exigua cell line and larval injection bioassays. Both bioassays led to similar results in the order of PA toxicity, indicating that the cell lines are a valuable tool for a first toxicity screen. Testing individual PAs, jacobine and Erucifoline were the most toxic PAs, suggesting their major role in plant defense against generalist herbivores.
CONCLUSIONS:
Senkirkine and seneciphylline were less toxic than jacobine and Erucifoline but more toxic than retrorsine. Senecionine was not toxic at the tested concentrations. For all toxic PAs, the free base form was more toxic than the N-oxide form. Our results demonstrate that structural variation of PAs influences their effectiveness in plant defense.
Erucifoline Description
Source: The herbs of Senecio argunensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
(1,5E,11E)-tridecatriene-7,9-diyne...

Catalog No: CFN95161
CAS No: 201012-14-8
Price: $318/10mg
2,3-Dehydrosilychristin

Catalog No: CFN95370
CAS No: 57499-41-9
Price: $318/5mg
Biatractylolide

Catalog No: CFN95205
CAS No: 182426-37-5
Price: $268/10mg
Isoeuphorbetin

Catalog No: CFN95207
CAS No: 50677-55-9
Price: $318/5mg
11-Oxomogroside IIA2

Catalog No: CFN95305
CAS No: 2170761-37-0
Price: $368/5mg
Gymnoside III

Catalog No: CFN95033
CAS No: 899430-03-6
Price: $238/10mg
Mucronulatol

Catalog No: CFN95386
CAS No: 20878-98-2
Price: $318/5mg
Physalin O

Catalog No: CFN95097
CAS No: 120849-18-5
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8622 mL 14.3111 mL 28.6221 mL 57.2443 mL 71.5553 mL
5 mM 0.5724 mL 2.8622 mL 5.7244 mL 11.4489 mL 14.3111 mL
10 mM 0.2862 mL 1.4311 mL 2.8622 mL 5.7244 mL 7.1555 mL
50 mM 0.0572 mL 0.2862 mL 0.5724 mL 1.1449 mL 1.4311 mL
100 mM 0.0286 mL 0.1431 mL 0.2862 mL 0.5724 mL 0.7156 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry. 2004 Apr;65(7):865-73.
Variation in pyrrolizidine alkaloid patterns of Senecio jacobaea.[Pubmed: 15081286]
We studied the variation in pyrrolizidine alkaloid (PA) patterns of lab-grown vegetative plants of 11 European Senecio jacobaea populations.
METHODS AND RESULTS:
Plants were classified as jacobine, Erucifoline, mixed or senecionine chemotypes based on presence and absence of the PAs jacobine or Erucifoline. Due to the presence of jacobine, total PA concentration in jacobine chemotypes was higher than in Erucifoline chemotypes. Both relative and absolute concentrations of individual PAs differed between half-sib and clonal families, which showed that variation in PA patterns had a genetic basis.
CONCLUSIONS:
Within most populations relative abundance of PAs varied considerably between individual plants. Most populations consisted either of the jacobine chemotype or of the Erucifoline chemotype, sometimes in combination with mixed or senecionine chemotypes.
Taxifolin

Catalog No: CFN98734
CAS No: 480-18-2
Price: $30/20mg
Scutellarein

Catalog No: CFN98557
CAS No: 529-53-3
Price: $60/20mg
Myricetin 3-O-beta-D-glucopyranoside

Catalog No: CFN80163
CAS No: 19833-12-6
Price: $413/5mg
(-)-Bilobalide

Catalog No: CFN99789
CAS No: 33570-04-6
Price: $40/20mg
Cryptochlorogenic acid

Catalog No: CFN99117
CAS No: 905-99-7
Price: $90/20mg
Notoginsenoside Fe

Catalog No: CFN93282
CAS No: 88105-29-7
Price: $100/20mg
Taraxasterol

Catalog No: CFN99074
CAS No: 1059-14-9
Price: $338/20mg
Umbelliferone

Catalog No: CFN97503
CAS No: 93-35-6
Price: $30/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Taxiphyllin

Catalog No: CFN98070
CAS No: 21401-21-8
Price: $ /
Tags: buy Erucifoline | Erucifoline supplier | purchase Erucifoline | Erucifoline cost | Erucifoline manufacturer | order Erucifoline | Erucifoline distributor