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Euphorbia factor L7a
Euphorbia factor L7a
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Euphorbia factor L7a
Price: $298 / 20mg
CAS No.: 93550-94-8
Catalog No.: CFN92885
Molecular Formula: C33H40O7
Molecular Weight: 548.7 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Euphorbia pekinensis Rupr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $111.4 / In-stock
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Description: Reference standards.
Euphorbia factor L7a Description
Source: The herbs of Euphorbia pekinensis Rupr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8225 mL 9.1124 mL 18.2249 mL 36.4498 mL 45.5622 mL
5 mM 0.3645 mL 1.8225 mL 3.645 mL 7.29 mL 9.1124 mL
10 mM 0.1822 mL 0.9112 mL 1.8225 mL 3.645 mL 4.5562 mL
50 mM 0.0364 mL 0.1822 mL 0.3645 mL 0.729 mL 0.9112 mL
100 mM 0.0182 mL 0.0911 mL 0.1822 mL 0.3645 mL 0.4556 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Proceedings of the 19th National Conference on Organic Analysis and Bioanalysis of the Chinese Chemical Society 2017
Analysis of Lathyrane Diterpenes as Modulators of P-Glycoprotein Dependent Multidrug Resistance.[Reference: WebLink]

METHODS AND RESULTS:
A series of lathyranediterpeneswere isolated or synthesized,and established on the basis of extensive spectroscopic methods,including two-dimensional NMR techniques.Stereo configuration and conformation of Euphorbia factor L1, Euphorbia factor L2, Euphorbia factor L7a, Euphorbia factor L7b, Euphorbia factor L8 and derivatives of L3 were analyzed by X-ray diffraction for the first time.The configuration of the unique isolathyrolditerpene Euphorbia factor L_(7b) was rectified from S* to R* at C-5.All compounds were examined as modulators of multidrug resistance on MCF-7/ADM cell lines in vitro.
CONCLUSIONS:
To obtain sufficient information on the structural characteristics of this class of compounds,the detailed fragmentation patterns of the lathyranediterpenes were studied with collision-induced dissociation(CID)–MS/MS using an ESI–quadrupole time-of-flight(QTOF)–MS/MS hybrid instrument in positive-ion mode.
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Palmatine

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Price: $40/20mg
Epimedin A

Catalog No: CFN99939
CAS No: 110623-72-8
Price: $128/20mg
Procyanidin A2

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Price: $238/10mg
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Vincristine sulfate

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Fisetin

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Moschamine

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Price: $218/5mg
Luteolin-7-O-glucoside

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