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Isonardoperoxide
Isonardoperoxide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isonardoperoxide
Price:
CAS No.: 205248-65-3
Catalog No.: CFN89350
Molecular Formula: C15H22O4
Molecular Weight: 266.33 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Oil
Source: The roots of Nardostachys chinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Isonardoperoxide shows strong antimalarial activity against Plasmodium falciparum malaria (6.0 × 10−7 M).
Targets: Antifection
In vitro:
Tetrahedron Letters, 1998, 39(11):1361-1364.
Novel antimalarial guaiane-type sesquiterpenoids from Nardostachys chinensis roots.[Reference: WebLink]

METHODS AND RESULTS:
Three guaiane-type sesquiterpenoids, nardoperoxide (1a), Isonardoperoxide (2a) and nardoxide (3), were isolated from Nardostachys chinensis roots. Their structures were elucidated by spectral means.
CONCLUSIONS:
Among them, two endoperoxides, nardoperoxide (1a) and Isonardoperoxide (2a), showed strong antimalarial activity against Plasmodium falciparum malaria (EC50 1.5 × 10−6 and 6.0 × 10−7 M, respectively).
Isonardoperoxide Description
Source: The roots of Nardostachys chinensis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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IF=14.548(2019)

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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

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Nature Plants. 2016 Dec 22;3: 16206.
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PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7547 mL 18.7737 mL 37.5474 mL 75.0948 mL 93.8685 mL
5 mM 0.7509 mL 3.7547 mL 7.5095 mL 15.019 mL 18.7737 mL
10 mM 0.3755 mL 1.8774 mL 3.7547 mL 7.5095 mL 9.3869 mL
50 mM 0.0751 mL 0.3755 mL 0.7509 mL 1.5019 mL 1.8774 mL
100 mM 0.0375 mL 0.1877 mL 0.3755 mL 0.7509 mL 0.9387 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN92652Zedoarondiol98644-24-7252.4C15H24O3
CFN95848Isozedoarondiol108887-68-9252.4C15H24O3
CFN92620Isoprocurcumenol102130-90-5234.3C15H22O2
CFN92647Procurcumenol21698-40-8234.3C15H22O2
CFN91614Epiprocurcumenol127214-97-5234.33C15H22O2
CFN92621Aerugidiol116425-35-5250.3C15H22O3
CFN92789Neoprocurcumenol102130-91-6234.3C15H22O2
CFN96368Torilolone13018-09-2252.4C15H24O3
CFN967928-O-Acetyltorilolone20482-21-7294.39C17H26O4
CFN96316Torilin13018-10-5376.5C22H32O5
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