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Isorhynchophyllic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isorhynchophyllic acid
Price:
CAS No.: 144525-05-3
Catalog No.: CFN98132
Molecular Formula: C21H26N2O4
Molecular Weight: 370.44 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: White cryst.
Source: The herbs of Uncaria rhynchophylla.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Isorhynchophyllic acid can significantly inhibit the proliferation of human cancer cells(A549, HepG2 and A2780 cells) with IC50 values being 5.8, 12.8 and 11.8 umol/L, respectively.
In vitro:
Chin. J. Nat. Med.,2016 Mar;14(3):232-5.
Two new ortho benzoquinones from Uncaria rhynchophylla.[Pubmed: 27025371]
The present study was designed to determine the chemical constituents of the stems and hooks of Uncaria rhynchophylla.
METHODS AND RESULTS:
The chemical constituents were isolated and purified from CH2Cl2 fraction by chromatography. Their structures were elucidated by spectroscopic analyses. Their cytotoxicity was tested using MTT method. Two new ortho benzoquinones, 3-diethylamino-5-methoxy-1, 2-benzoquinone (1) and 3-ethylamino-5-methoxy-1, 2-benzoquinone (2), together with a known compound Isorhynchophyllic acid (3) were isolated from U. rhynchophylla. These compounds were evaluated for their cytotoxicity against cancer cells A549, HepG2 and A2780.
CONCLUSIONS:
Compounds 1 and 2 were new ortho benzoquinones and showed weak antiproliferative activities on A549, HepG2 and A2780 cells. Compound 3 significantly inhibited the proliferation of A549, HepG2 and A2780 cells with IC50 values being 5.8, 12.8 and 11.8 μmol·L(-1), respectively.
Isorhynchophyllic acid Description
Source: The herbs of Uncaria rhynchophylla.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6995 mL 13.4975 mL 26.9949 mL 53.9898 mL 67.4873 mL
5 mM 0.5399 mL 2.6995 mL 5.399 mL 10.798 mL 13.4975 mL
10 mM 0.2699 mL 1.3497 mL 2.6995 mL 5.399 mL 6.7487 mL
50 mM 0.054 mL 0.2699 mL 0.5399 mL 1.0798 mL 1.3497 mL
100 mM 0.027 mL 0.135 mL 0.2699 mL 0.5399 mL 0.6749 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Astragalin

Catalog No: CFN98733
CAS No: 480-10-4
Price: $80/20mg
Taxifolin

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Momordicoside K

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