Science | Nature | Cell | View More
Natural Products
Kuguacin R
Kuguacin R
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Kuguacin R
Price:
CAS No.: 191097-54-8
Catalog No.: CFN92075
Molecular Formula: C30H48O4
Molecular Weight: 472.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The fruits of Momordica charantia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Utah State University (USA)
  • Ain Shams University (Egypt)
  • Universidade Católica Portuguesa (Portugal)
  • VIB Department of Plant Systems... (Belgium)
  • The Australian National University (Australia)
  • Shanghai University of TCM (China)
  • Indian Institute of Science (India)
  • Regional Crop Research Institute (Korea)
  • Chang Gung University (Taiwan)
  • Chinese University of Hong Kong (China)
  • University of Wuerzburg (Germany)
  • More...
Package
Featured Products
Astragaloside III

Catalog No: CFN99174
CAS No: 84687-42-3
Price: $268/20mg
Epimedin B

Catalog No: CFN99940
CAS No: 110623-73-9
Price: $128/20mg
Germacrene D

Catalog No: CFN93281
CAS No: 37839-63-7
Price: $ / mg
1,4-Cineole

Catalog No: CFN70116
CAS No: 470-67-7
Price: $30/20mg
Honokiol

Catalog No: CFN99902
CAS No: 35354-74-6
Price: $30/20mg
Ferruginol

Catalog No: CFN92178
CAS No: 514-62-5
Price: $ / mg
Aristolochic acid A

Catalog No: CFN99505
CAS No: 313-67-7
Price: $80/20mg
Isorhamnetin

Catalog No: CFN98735
CAS No: 480-19-3
Price: $60/20mg
(E)-Aldosecologanin

Catalog No: CFN97737
CAS No: 471271-55-3
Price: $333/5mg
Silybin A

Catalog No: CFN95149
CAS No: 22888-70-6
Price: $318/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Kuguacin R is a natural product from Momordica charantia.
Kuguacin R Description
Source: The fruits of Momordica charantia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
3-Oxo-4-benzyl-3,4-dihydro-1H-pyrr...

Catalog No: CFN95293
CAS No: 60026-28-0
Price: $413/5mg
Quercetin 7-O-(6''-O-malonyl)-beta...

Catalog No: CFN95208
CAS No: 98767-37-4
Price: $388/5mg
Securoside A

Catalog No: CFN95294
CAS No: 107172-40-7
Price: $318/5mg
Corymboside

Catalog No: CFN95292
CAS No: 73543-87-0
Price: $318/10mg
Fargesol

Catalog No: CFN95027
CAS No: 128855-64-1
Price: $318/20mg
(-)-Epiafzelechin 3-O-gallate

Catalog No: CFN95081
CAS No: 108907-43-3
Price: $388/5mg
Orthosiphol A

Catalog No: CFN95442
CAS No: 142741-25-1
Price: $318/5mg
Quercetin 3,7-diglucoside

Catalog No: CFN95408
CAS No: 6892-74-6
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5775 mL 21.1551 mL 42.3101 mL 52.8877 mL
5 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
10 mM 0.2116 mL 1.0578 mL 2.1155 mL 4.231 mL 5.2888 mL
50 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Fitoterapia. 2014 Jun;95:75-82.
Cucurbitane-type triterpenoids from the stems and leaves of Momordica charantia.[Pubmed: 24631764 ]

METHODS AND RESULTS:
Six new cucurbitane-type triterpenoids, karavilagenin F (1), karavilosides XII and XIII (2, 3), momordicines VI, VII, and VIII (4, 5 and 6), along with four known ones, 5β,19-epoxy-25-methoxycucurbita-6,23-diene-3β,19-diol (7), 5β,19-epoxycucurbita-6, 23-diene-3β,19,25-triol (8), Kuguacin R (9), and (19R,23E)-5β,19-epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol (10), were isolated from the stems and leaves of Momordica charantia L. Their chemical structures were elucidated by extensive 1D NMR and 2D NMR (HSQC, HMBC, COSY, and ROESY), MS experiments, and CD spectrum.
CONCLUSIONS:
Compound 6 showed weak cytotoxicity against five human cancer cells lines with IC50 values of 14.3-20.5μmol/L.
Astragaloside III

Catalog No: CFN99174
CAS No: 84687-42-3
Price: $268/20mg
Epimedin B

Catalog No: CFN99940
CAS No: 110623-73-9
Price: $128/20mg
Germacrene D

Catalog No: CFN93281
CAS No: 37839-63-7
Price: $ / mg
1,4-Cineole

Catalog No: CFN70116
CAS No: 470-67-7
Price: $30/20mg
Honokiol

Catalog No: CFN99902
CAS No: 35354-74-6
Price: $30/20mg
Ferruginol

Catalog No: CFN92178
CAS No: 514-62-5
Price: $ / mg
Aristolochic acid A

Catalog No: CFN99505
CAS No: 313-67-7
Price: $80/20mg
Isorhamnetin

Catalog No: CFN98735
CAS No: 480-19-3
Price: $60/20mg
(E)-Aldosecologanin

Catalog No: CFN97737
CAS No: 471271-55-3
Price: $333/5mg
Silybin A

Catalog No: CFN95149
CAS No: 22888-70-6
Price: $318/20mg
Tags: buy Kuguacin R | Kuguacin R supplier | purchase Kuguacin R | Kuguacin R cost | Kuguacin R manufacturer | order Kuguacin R | Kuguacin R distributor