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N-Methylcorydinium iodide
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Product Name N-Methylcorydinium iodide
Price:
CAS No.: 4668-64-6
Catalog No.: CFN92891
Molecular Formula: C21H26NO4
Molecular Weight: 356.43 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The aerial parts of Glaucium oxylobum BOISS. et BUSHE.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: N-Methylcorydinium iodide is a natural product from Glaucium oxylobum BOISS. et BUSHE.
N-Methylcorydinium iodide Description
Source: The aerial parts of Glaucium oxylobum BOISS. et BUSHE.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8056 mL 14.028 mL 28.056 mL 56.112 mL 70.14 mL
5 mM 0.5611 mL 2.8056 mL 5.6112 mL 11.2224 mL 14.028 mL
10 mM 0.2806 mL 1.4028 mL 2.8056 mL 5.6112 mL 7.014 mL
50 mM 0.0561 mL 0.2806 mL 0.5611 mL 1.1222 mL 1.4028 mL
100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5611 mL 0.7014 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Collect. Czech. Chem. Commun. 1985, 50, 854-860.
Quaternary alkaloids from Glaucium oxylobum BOISS. et BUSHE.[Reference: WebLink]

METHODS AND RESULTS:
From the fraction of quaternary alkaloids of the aerial part of Glaucium oxylobum BOISS. et BUSHE (-)-trans-N-rnethylcanadinium iodide was isolated as the main alkaloid after conversion to iodides, and, in a smaller amount, (+)-N-Methylcorydinium iodide, detected for the first time in Papaveraceae, further (-)-trans-N-methylstylopinium iodide, magnoflorine iodide and a new quaternary alkaloid, N-methyldomesticinium iodide, isolated for the first time as a natural substance. In the roots, magnoflorine iodide accompanied by (+)-N-Methylcorydinium iodide represented the main component of the quaternary fraction. From both plant parts corytuberine was also isolated for the first time.
CONCLUSIONS:
In the tertiary fraction of alkaloids (+)-corydine, protopine and allocryptopine were the major components, accompanied by smaller amounts of sanguinarine, chelerythrine, chelirubine, domesticine, isoboldine and scoulerine. In the fraction of quaternary protoberberines coptisine, berberine and traces of corysamine were detected.
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