Science | Nature | Cell | View More
Natural Products
Nemorensine
Nemorensine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Nemorensine
Price:
CAS No.: 50906-96-2
Catalog No.: CFN00387
Molecular Formula: C18H27NO5
Molecular Weight: 337.41 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Senecio nemoresis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Technical University of Denmark (Denmark)
  • Shanghai Institute of Biochemis... (China)
  • Kamphaengphet Rajabhat University (Thailand)
  • University of Melbourne (Australia)
  • University of the Basque Country (Spain)
  • Fraunhofer-Institut für Moleku... (Germany)
  • Siksha O Anusandhan University (India)
  • University of Liège (Belgium)
  • Rio de Janeiro State University (Brazil)
  • University of Illinois at Chicago (USA)
  • Mendel University in Brno (Czech Republic)
  • More...
Package
Featured Products
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
Limonin

Catalog No: CFN99280
CAS No: 1180-71-8
Price: $40/20mg
Rhaponiticin

Catalog No: CFN98569
CAS No: 155-58-8
Price: $60/20mg
Isoimperatorin

Catalog No: CFN99107
CAS No: 482-45-1
Price: $40/20mg
8-Gingerol

Catalog No: CFN99131
CAS No: 23513-08-8
Price: $118/20mg
Pallidol

Catalog No: CFN92341
CAS No: 105037-88-5
Price: $318/10mg
Scoparone

Catalog No: CFN99314
CAS No: 120-08-1
Price: $30/20mg
Calenduloside E

Catalog No: CFN91169
CAS No: 26020-14-4
Price: $268/10mg
Butein

Catalog No: CFN98776
CAS No: 487-52-5
Price: $100/20mg
Robinin

Catalog No: CFN98375
CAS No: 301-19-9
Price: $318/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Analytical Letters, 2006 , 22 (15) :3041-3055.
Indirect Determination of Pyrrolizidine Alkaloids by Flame Atomic Absorption Spectrometry[Reference: WebLink]
This paper studies the formation and extraction of ion pairs of some alkaloids derived from pyrrolizidine.
METHODS AND RESULTS:
The substances studied are Nemorensine, Platyphylline, Senecionine and Seneciphylline, and the ion pairs studied and extracted are formed with Bil4. The method consists of extracting an ion pair between the organic base and the inorganic complex, the metal is measured in the organic phase (1,2 dichloroethane) by Flame AAS. The optimal experimental conditions, pH, concentration of BiI4 , shaking time, phase ratio, number of extractions, and the range of calibration are studied for these substances. The linear range in organic phase is 0.13–1.91 mg.mL.
CONCLUSIONS:
The standard deviation of the method varies between 2.4–3.2%, depending on the substance analyzed. The interferences produced by various substances are studied.
Nemorensine Description
Source: The herbs of Senecio nemoresis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New compound 13

Catalog No: CFN95374
CAS No: N/A
Price: $318/5mg
Murracarpin

Catalog No: CFN95409
CAS No: 120786-76-7
Price: $413/5mg
Foliachinenoside C

Catalog No: CFN95361
CAS No: 1041180-87-3
Price: $368/5mg
Licoflavanone

Catalog No: CFN95213
CAS No: 119240-82-3
Price: $413/5mg
Grosvenorin 2''-glucoside

Catalog No: CFN95282
CAS No: N/A
Price: $318/5mg
6alpha-Hydroxydehydropachymic acid

Catalog No: CFN95412
CAS No: 176390-67-3
Price: $413/5mg
Symplocoside

Catalog No: CFN95552
CAS No: 76502-76-6
Price: $318/5mg
Methyl neochebulinate

Catalog No: CFN95201
CAS No: 1236310-34-1
Price: $398/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9638 mL 14.8188 mL 29.6375 mL 59.2751 mL 74.0938 mL
5 mM 0.5928 mL 2.9638 mL 5.9275 mL 11.855 mL 14.8188 mL
10 mM 0.2964 mL 1.4819 mL 2.9638 mL 5.9275 mL 7.4094 mL
50 mM 0.0593 mL 0.2964 mL 0.5928 mL 1.1855 mL 1.4819 mL
100 mM 0.0296 mL 0.1482 mL 0.2964 mL 0.5928 mL 0.7409 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Org Chem. 1999 Jul 23;64(15):5542-5546.
Enantiospecific Synthesis of (+)-Nemorensic Acid, a Necic Acid Component of the Macropyrrolizidine Alkaloid, Nemorensine.[Pubmed: 11674618]

METHODS AND RESULTS:
A concise enantiospecific synthesis of nemorensic acid 3, a necic acid component of the macropyrrolizidine alkaloid Nemorensine 2, isolated from Senecio nemorensis L., is described. Reaction of an epsilon-halo-alpha,beta-unsaturated ester (8), readily accessible from a monoterpene (-)-carvone, with samarium iodide gave a fragmentation product (9), where a carbon-carbon bond cleavage reaction occurred between the gamma and delta positions of the carbonyl group, regioselectively.
CONCLUSIONS:
Deprotection of the silyl group of 9 brought about an intramolecular cyclization to provide tetrahydrofuran derivatives (10), which, upon chemical modification of the side chain, gave nemorensic acid.
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
Limonin

Catalog No: CFN99280
CAS No: 1180-71-8
Price: $40/20mg
Rhaponiticin

Catalog No: CFN98569
CAS No: 155-58-8
Price: $60/20mg
Isoimperatorin

Catalog No: CFN99107
CAS No: 482-45-1
Price: $40/20mg
8-Gingerol

Catalog No: CFN99131
CAS No: 23513-08-8
Price: $118/20mg
Pallidol

Catalog No: CFN92341
CAS No: 105037-88-5
Price: $318/10mg
Scoparone

Catalog No: CFN99314
CAS No: 120-08-1
Price: $30/20mg
Calenduloside E

Catalog No: CFN91169
CAS No: 26020-14-4
Price: $268/10mg
Butein

Catalog No: CFN98776
CAS No: 487-52-5
Price: $100/20mg
Robinin

Catalog No: CFN98375
CAS No: 301-19-9
Price: $318/5mg
Tags: buy Nemorensine | Nemorensine supplier | purchase Nemorensine | Nemorensine cost | Nemorensine manufacturer | order Nemorensine | Nemorensine distributor