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Nortetraphyllicine
Nortetraphyllicine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Nortetraphyllicine
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CAS No.: 68160-76-9
Catalog No.: CFN97163
Molecular Formula: C19H22N2O
Molecular Weight: 294.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Rauvolfia verticillata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Nortetraphyllicine is a natural product from Rauvolfia verticillata.
Nortetraphyllicine Description
Source: The roots of Rauvolfia verticillata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3967 mL 16.9837 mL 33.9674 mL 67.9348 mL 84.9185 mL
5 mM 0.6793 mL 3.3967 mL 6.7935 mL 13.587 mL 16.9837 mL
10 mM 0.3397 mL 1.6984 mL 3.3967 mL 6.7935 mL 8.4918 mL
50 mM 0.0679 mL 0.3397 mL 0.6793 mL 1.3587 mL 1.6984 mL
100 mM 0.034 mL 0.1698 mL 0.3397 mL 0.6793 mL 0.8492 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med 1978; 33(4): 360-364.
Root alkaloids of Rauwolfia cumminsii Stapf[Reference: WebLink]
The leaves of Rauwolfia cumminsii Stapf yield at least 12 indole alkaloids.
METHODS AND RESULTS:
Two E–seco indole alkaloids (corynantheol and corynantheal), seven ajmalantype dihydroindole alkaloids (endolobine, norpurpeline, dihydronorpurpeline, normitoridine, norseredamine, Nortetraphyllicine and seredamine–17–O–(3', 4', 5') trimethoxybenzoate), two sarpagan alkaloids (normacusine B–O–methyl and an incompletely characterised compound) and the indoline alkaloid picrinine were isolated.
CONCLUSIONS:
The apparent scarcity of Namethylated indoline alkaloids in the plant may prove to be significant.
CFN93513Ajmaline4360-12-7326.4C20H26N2O2
CFN92581Ajmalidine639-30-5324.4C20H24N2O2
CFN92611Ajmalan-17-one3911-19-1322.4C20H22N2O2
CFN92503Ajmalimine59846-31-0520.6C30H36N2O6
CFN92504Rauvomitin466-57-9502.6C30H34N2O5
CFN96749Rauvotetraphylline D1422506-52-2390.48C24H26N2O3
CFN97757Vinorine34020-07-0334.42C21H22N2O2
CFN97910Alstoyunine E1188932-15-1350.4C21H22N2O3
CFN97762Raucaffricine31282-07-2512.56C27H32N2O8
CFN98673Perakine4382-56-3350.4 C21H22N2O3
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