Science | Nature | Cell | View More
Natural Products
Ophiopogonanone A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ophiopogonanone A
Price: $318 / 5mg
CAS No.: 75239-63-3
Catalog No.: CFN96337
Molecular Formula: C18H16O6
Molecular Weight: 328.3 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The tubers of Ophiopogon japonicus(Thunb) Ker-Gawl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $270.3 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Sao Paulo (Brazil)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Institute of Bioorganic Chemist... (Poland)
  • Mahatma Gandhi University (India)
  • Institute of Tropical Disease U... (Indonesia)
  • University of Illinois (USA)
  • Osmania University (India)
  • Universidad de La Salle (Mexico)
  • National Chung Hsing University (Taiwan)
  • Universite Libre de Bruxelles (Belgium)
  • National Cancer Institute (USA)
  • More...
Package
Featured Products
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Nootkatone

Catalog No: CFN98699
CAS No: 4674-50-4
Price: $40/20mg
Ferulic acid

Catalog No: CFN99158
CAS No: 1135-24-6
Price: $40/20mg
Phlorizin

Catalog No: CFN97038
CAS No: 60-81-1
Price: $30/20mg
Ginsenoside Rb2

Catalog No: CFN99965
CAS No: 11021-13-9
Price: $100/20mg
Isorhoifolin

Catalog No: CFN98927
CAS No: 552-57-8
Price: $318/10mg
Lasiocarpine

Catalog No: CFN00289
CAS No: 303-34-4
Price: $ /
trans-3-Oxo-alpha-ionol

Catalog No: CFN92428
CAS No: 896107-70-3
Price: $ / mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Ellagic acid

Catalog No: CFN98716
CAS No: 476-66-4
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
In vitro:
Chinese Journal of Natural Medicines,2008,6(3):201-4.
Homoisoflavonoids from Ophiopogon japonicus and Its Oxygen Free Radicals(OFRs) Scavenging Effects[Pubmed: 12444717]
To investigate the OFRs scavenging activities of homoisoflavonoids from the fibrous root of Ophiopogon japonicus.
METHODS AND RESULTS:
The scavenging effect of homoisoflavonoids isolated from O.japonicus extracts was examined on superoxide anion(O2·-),hydroxyl radical(·OH),and hydrogen peroxide(H2O2) by chemiluminescence. Ten homoisoflavonoids were obtained from O.japonicus extracts.They were identified as methylOphiopogonanone A(1),methylophiopogonanone B(2),Ophiopogonanone A(3),ophiopogonanone E(4),5,7-dihydroxy-6,8-dimethyl-3-(4'-hydroxy-3',5'-methoxybenzyl) chroman-4-one(5),methylophiopogonone A(6),methylophiopogonone B(7),desmethylisoophiopogonone B(8),5,7,2'-trihydroxy-8-methyl-3-(3',4'-methylenedioxybenzyl) chromone(9) and 5,7,2'-trihydroxy-6,8-dimethyl-3-(3',4'-methylenedioxybenzyl) chromone(10).
CONCLUSIONS:
Compounds 8 and 9 were firstly isolated from O.japonicus.The majority of homoisoflavonoids could scavenge ·OH and H2O2 in vitro to a certain extent,and their bioactivities should be related with the respective structures.
Ophiopogonanone A Description
Source: The tubers of Ophiopogon japonicus(Thunb) Ker-Gawl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Selaginellin

Catalog No: CFN95030
CAS No: 941269-84-7
Price: $338/5mg
5-Hydroxy-7,8-dimethoxy (2R)-flava...

Catalog No: CFN95209
CAS No: 942626-74-6
Price: $318/10mg
Polygalin C

Catalog No: CFN95118
CAS No: 934768-05-5
Price: $288/5mg
3-Oxo-4-benzyl-3,4-dihydro-1H-pyrr...

Catalog No: CFN95293
CAS No: 60026-28-0
Price: $413/5mg
Methyl lucidenate G

Catalog No: CFN95058
CAS No: 102607-20-5
Price: $413/5mg
Obovatol

Catalog No: CFN95054
CAS No: 83864-78-2
Price: $318/5mg
Oxytroflavoside E

Catalog No: CFN95464
CAS No: 1391144-84-5
Price: $318/5mg
1-Methoxycarbonyl-beta-carboline-N...

Catalog No: CFN95023
CAS No: 74690-74-7
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.046 mL 15.23 mL 30.4599 mL 60.9199 mL 76.1499 mL
5 mM 0.6092 mL 3.046 mL 6.092 mL 12.184 mL 15.23 mL
10 mM 0.3046 mL 1.523 mL 3.046 mL 6.092 mL 7.615 mL
50 mM 0.0609 mL 0.3046 mL 0.6092 mL 1.2184 mL 1.523 mL
100 mM 0.0305 mL 0.1523 mL 0.3046 mL 0.6092 mL 0.7615 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical & Pharmaceutical Bulletin, 2008,28(7):2039-44.
Studies on the Constituents of Ophiopogonis Tuber. VI. Structures of Homoisoflavonoids. (2)[Reference: WebLink]

METHODS AND RESULTS:
New homoisoflavonoidal compounds, ophiopogonone A (Va), isoophiopogonone A (VIa), ophiopogonone B (VIIa), desmethylisoophiopogonone B (VIII) and Ophiopogonanone A (IXa) were isolated as constitutents of Ophiopogonis tuber (Ophiopogon japonicus KER-GAWLER var. genuinus MAXIM., Liliaceae), and their chemical structures were elucidated as 5, 7-dihydroxy-6-methyl-3-(3, 4-methylenedioxybenzyl) chromone, 5, 7-dihydroxy-8-methyl-3-(3, 4-methylenedioxybenzyl) chromone, 5, 7-dihydroxy-6-methyl-3-(4-methoxybenzyl) chromone, 5, 7-dihydroxy-8-methyl-3-(4-hydroxybenzyl) chromone and 5, 7-dihydroxy-6-methyl-3-(3, 4-methylenedioxybenzyl) chroman-4-one, respectively, by chemical and spectral studies.
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Nootkatone

Catalog No: CFN98699
CAS No: 4674-50-4
Price: $40/20mg
Ferulic acid

Catalog No: CFN99158
CAS No: 1135-24-6
Price: $40/20mg
Phlorizin

Catalog No: CFN97038
CAS No: 60-81-1
Price: $30/20mg
Ginsenoside Rb2

Catalog No: CFN99965
CAS No: 11021-13-9
Price: $100/20mg
Isorhoifolin

Catalog No: CFN98927
CAS No: 552-57-8
Price: $318/10mg
Lasiocarpine

Catalog No: CFN00289
CAS No: 303-34-4
Price: $ /
trans-3-Oxo-alpha-ionol

Catalog No: CFN92428
CAS No: 896107-70-3
Price: $ / mg
Naringenin chalcone

Catalog No: CFN90606
CAS No: 73692-50-9
Price: $168/20mg
Ellagic acid

Catalog No: CFN98716
CAS No: 476-66-4
Price: $30/20mg
Tags: buy Ophiopogonanone A | Ophiopogonanone A supplier | purchase Ophiopogonanone A | Ophiopogonanone A cost | Ophiopogonanone A manufacturer | order Ophiopogonanone A | Ophiopogonanone A distributor