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Paniculoside I
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Product Name Paniculoside I
Price:
CAS No.: 60129-63-7
Catalog No.: CFN97018
Molecular Formula: C26H40O8
Molecular Weight: 480.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Stevia rebaudiana
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Biological Activity
Description: Paniculoside I is a natural product from Stevia rebaudiana.
Paniculoside I Description
Source: The herbs of Stevia rebaudiana
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0807 mL 10.4037 mL 20.8073 mL 41.6146 mL 52.0183 mL
5 mM 0.4161 mL 2.0807 mL 4.1615 mL 8.3229 mL 10.4037 mL
10 mM 0.2081 mL 1.0404 mL 2.0807 mL 4.1615 mL 5.2018 mL
50 mM 0.0416 mL 0.2081 mL 0.4161 mL 0.8323 mL 1.0404 mL
100 mM 0.0208 mL 0.104 mL 0.2081 mL 0.4161 mL 0.5202 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical & Pharmaceutical Bulletin , 2008 , 25 (11) :2895-2899.
Application of ^<13>C Nuclear Magnetic Resonance Spectroscopy to Chemistry of Glycosides : Structures of Paniculosides-I, -II, -III, -IV, and -V, Diterpene Glucosides of Stevia paniculata LAG.[Reference: WebLink]
From the aerial part of Stevia paniculata (Compositae), five new diterpene glucosides, named Paniculoside I, Paniculoside II, Paniculoside III, Paniculoside IV, and Paniculoside V(5-9) were isolated.
METHODS AND RESULTS:
On comparison of ^<13>C nuclear magnetic resonance spectra of these glucosides with those of the aglycones, ent-15α-hydroxykaur-16-en-19-oic acid (1) [as methyl ester (17)], ent-11α-hydroxy-15-oxokaur-16-en-19-oic acid (2), ent-11α, 15α-dihydroxykaur-16-en-19-oic acid (3), and ent-16β, 17-dihydroxykauran-19-oic acid (4) as well as some model glucosides, paniculosides I-IV (5-8) can be formulated as β-glucopyranosyl ester of 1,3,2,and 4,respectively and paniculoside-V (9) can be represented by 15-O-β-glucopyranoside of 5.
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Rutaecarpine

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