| Structure Identification: |
| 《Journal of Jinan University(Natural Science & Medicine Edition)》 2014-01 | | Chemical constituents of Paris polyphylla var. yunnanensis[Reference: WebLink] | The chemical constituents of Paris polyphylla var. yunnanensis were isolated by several chromatographic methods,including silica gel,Sephadex LH-20,ODS CC and preparation HPLC.
METHODS AND RESULTS:
Thirteen compounds were obtained from the 30% ethanol eluting fraction of macroporous resin and their structures were elucidated by their spectral data and physicochemical properties,which were identified as calonysterone( 1),glycoside St-J( 2),methyl ester of glycoside St-J( 3),cussonoside B( 4),methyl 3, 4-dihydroxybenzoate( 5),α-ecdysone( 6),20-hydroxyecdysone( 7),pinnatasterone( 8),polyphyllin H( 9),polyphyllin Ⅶ( 10),Parisaponin I( 11),parisyunnanoside B( 12),polyphyllin Ⅱ( 13).
Among them,compounds 1- 5 were obtained from the genus Paris for the first time,and 1- 6 were isolated from this plant for the first time. | | Bioorg Med Chem Lett. 2003 Mar 24;13(6):1101-6. | | Protective effects of steroid saponins from Paris polyphylla var. yunnanensis on ethanol- or indomethacin-induced gastric mucosal lesions in rats: structural requirement for activity and mode of action.[Reference: WebLink] |
METHODS AND RESULTS:
A new furostanol-type steroid saponin, Parisaponin I (5), together with two known furostanol-type steroid saponins, trigofoenoside A (6) and protogracillin (7), were isolated from the active fraction. |
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