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Polyporusterone A
Polyporusterone A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Polyporusterone A
Price: $318 / 10mg
CAS No.: 141360-88-5
Catalog No.: CFN91564
Molecular Formula: C28H46O6
Molecular Weight: 478.7 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The fruit body of Polyporus umbellatus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $174.2 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Polymer ketone A has the effect of promoting hair regeneration.Polyporuserone A has inhibitory activities against AAPH-induced lysis of red blood cells.Polyporuserone A is cytotoxic to leukemia 1210 cell proliferation.
In vitro:
Biol Pharm Bull . 1999 Nov;22(11):1189-1192.
Studies of the active substances in herbs used for hair treatment. II. Isolation of hair regrowth substances, acetosyringone and polyporusterone A and B, from Polyporus umbellatus Fries[Pubmed: 10598026]
Fractionation of the 50% ethanol extract of Polyporus umbellatus Fries by column chromatography on Amberlite XAD-2, silica gel, Sephadex LH-20 and octadecyl silica gel (ODS) (C18)) monitored by a hair-regrowth activity assay, afforded three active principles, 1, 2 and 3. The structures of 1, 2 and 3 were determined as acetosyringone, Polyporusterone A, and polyporusterone B by comparison of their spectral data with that of authentic samples, respectively. The effects of several compounds related to acetosyringone, 3,4-dihydroxybenzaldehyde or Polyporusterone A on hair regrowth were also investigated.
Chem Pharm Bull (Tokyo) . 1992 Jan;40(1):143-147.
Studies on constituents of fruit body of Polyporus umbellatus and their cytotoxic activity[Pubmed: 1576664]
From the crude drug Chorei, the fruit body of Polyporus umbellatus, seven new components named Polyporusterone A, B, C, D, E, F and G, were isolated and their structures were determined on the basis of the spectral data. These compounds showed cytotoxic action on leukemia 1210 cell proliferation.
Polyporusterone A Description
Source: The fruit body of Polyporus umbellatus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.089 mL 10.445 mL 20.8899 mL 41.7798 mL 52.2248 mL
5 mM 0.4178 mL 2.089 mL 4.178 mL 8.356 mL 10.445 mL
10 mM 0.2089 mL 1.0445 mL 2.089 mL 4.178 mL 5.2225 mL
50 mM 0.0418 mL 0.2089 mL 0.4178 mL 0.8356 mL 1.0445 mL
100 mM 0.0209 mL 0.1044 mL 0.2089 mL 0.4178 mL 0.5222 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Biol Pharm Bull . 1999 Nov;22(11):1189-1192.
Studies of the active substances in herbs used for hair treatment. II. Isolation of hair regrowth substances, acetosyringone and polyporusterone A and B, from Polyporus umbellatus Fries[Pubmed: 10598026]
Fractionation of the 50% ethanol extract of Polyporus umbellatus Fries by column chromatography on Amberlite XAD-2, silica gel, Sephadex LH-20 and octadecyl silica gel (ODS) (C18)) monitored by a hair-regrowth activity assay, afforded three active principles, 1, 2 and 3. The structures of 1, 2 and 3 were determined as acetosyringone, Polyporusterone A, and polyporusterone B by comparison of their spectral data with that of authentic samples, respectively. The effects of several compounds related to acetosyringone, 3,4-dihydroxybenzaldehyde or Polyporusterone A on hair regrowth were also investigated.
Chem Pharm Bull (Tokyo) . 1992 Jan;40(1):143-147.
Studies on constituents of fruit body of Polyporus umbellatus and their cytotoxic activity[Pubmed: 1576664]
From the crude drug Chorei, the fruit body of Polyporus umbellatus, seven new components named Polyporusterone A, B, C, D, E, F and G, were isolated and their structures were determined on the basis of the spectral data. These compounds showed cytotoxic action on leukemia 1210 cell proliferation.
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