Qingdainone | CAS:97457-31-3 | Manufacturer ChemFaces

Qingdainone

ChemFaces products have been cited in many studies from excellent and top scientific journals

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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Qingdainone Description

Source:	The leaves of Isatis indigotica
Solvent:	DMSO, Pyridine, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Yao Xue Xue Bao, 1985, 20(1):45-51.

Minor constituents of qing dai, a traditional Chinese medicine. I. Isolation, structural determination and synthesis of tryptanthrin and qingdainone.[Reference: WebLink]

METHODS AND RESULTS:
The study of Qing Dai, a traditional Chinese medicine, has resulted in the isolation of eight minor constituents Ⅲ～Ⅹ(3.3×10~(-5)～,4.2×10~(-4)%) after removing of the two major constituents Ⅰ (indigotin) and Ⅱ (indirubin). Constituent Ⅲ (C_(15)H_8 N_2O_2) was found to be identical to the known compound indolo [-2,1b]-quinazoline6,12-dione (tryptanthrin). Constituent Ⅳ (C_(23)H_(13)N_3O_2) was assigned on the basis of spectrometric data to have structure Ⅳ and confirmed by condensation of Ⅲ with diacetylindoxyl.
CONCLUSIONS:
It was first found from plant origin and designated Qingdainone. Ⅲ and Ⅳ were synthesized and found to be both active in test on melanoma B_(16) and Ⅳ also showed inhibitory action against Lewis lung carcinoma in mice.Structure determination of constituents Ⅴ～Ⅹ is in progress.

Product Name	Qingdainone
Price:
CAS No.:	97457-31-3
Catalog No.:	CFN70470
Molecular Formula:	C₂₃H₁₃N₃O₂
Molecular Weight:	363.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The leaves of Isatis indigotica
Solvent:	DMSO, Pyridine, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.7518 mL	13.7589 mL	27.5179 mL	55.0358 mL	68.7947 mL
5 mM	0.5504 mL	2.7518 mL	5.5036 mL	11.0072 mL	13.7589 mL
10 mM	0.2752 mL	1.3759 mL	2.7518 mL	5.5036 mL	6.8795 mL
50 mM	0.055 mL	0.2752 mL	0.5504 mL	1.1007 mL	1.3759 mL
100 mM	0.0275 mL	0.1376 mL	0.2752 mL	0.5504 mL	0.6879 mL

CFN89343	Bruceantinoside A	79439-85-3	710.71	C₃₄H₄₆O₁₆
CFN92733	Toddaculine	4335-12-0	274.3	C₁₆H₁₈O₄
CFN95135	5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA)	79559-61-8	328.4	C₂₀H₂₄O₄
CFN95599	Abiesinol B	1190070-89-3	558.5	C₃₀H₂₂O₁₁