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Seneciphyllinine
Seneciphyllinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Seneciphyllinine
Price:
CAS No.: 90341-45-0
Catalog No.: CFN00420
Molecular Formula: C20H25NO6
Molecular Weight: 375.42 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Gynura segetum (Lour.) Merr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Seneciphyllinine is a natural product from Gynura segetum (Lour.) Merr.
Seneciphyllinine Description
Source: The herbs of Gynura segetum (Lour.) Merr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6637 mL 13.3184 mL 26.6368 mL 53.2737 mL 66.5921 mL
5 mM 0.5327 mL 2.6637 mL 5.3274 mL 10.6547 mL 13.3184 mL
10 mM 0.2664 mL 1.3318 mL 2.6637 mL 5.3274 mL 6.6592 mL
50 mM 0.0533 mL 0.2664 mL 0.5327 mL 1.0655 mL 1.3318 mL
100 mM 0.0266 mL 0.1332 mL 0.2664 mL 0.5327 mL 0.6659 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Yao Xue Xue Bao. 1990;25(3):191-7.
[Studies on the alkaloids of Gynura segetum (Lour.) Merr].[Pubmed: 2239333]

METHODS AND RESULTS:
Six alkaloids were isolated from Gynura segetum (Lour.) Merr. Four of them were identified. Alkaloids I and II were identified as known senecionine and seneciphylline, respectively. Alkaloids III and IV were found to be new compounds named Seneciphyllinine and (E)-seneciphylline respectively.
CONCLUSIONS:
Their structures were confirmed on the basis of spectral data (UV, IR, MS, 1HNMR, 13CNMR, C-H COSY).
CFN00418Senecionine N-oxide13268-67-2351.17C18H25NO6
CFN00420Seneciphyllinine90341-45-0375.42C20H25NO6
CFN00421Riddelline23246-96-0349.38C18H23NO6
CFN00469Riddelline N-oxide75056-11-0365.4C18H23NO7
CFN00422Spartioidine520-59-2333.38C18H23NO5
CFN0047818-HydroxyspartioidineN/A349.4C18H23NO6
CFN00424Senkirkine2318-18-5365.42C19H27NO6
CFN98618Seneciphylline N-oxide38710-26-8349.4 C18H23NO6
CFN98747Seneciphylline480-81-9333.4 C18H23NO5
CFN00363Crotafoline38494-87-0351.40C18H25NO6
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