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Shegansu B
Shegansu B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Shegansu B
Price:
CAS No.: 291535-65-4
Catalog No.: CFN92424
Molecular Formula: C30H26O8
Molecular Weight: 514.5 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Gnetum montanum Markgr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
Targets: Influenza virus
In vitro:
Planta Med. 2010 Nov;76(16):1874-6.
In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.[Pubmed: 20539973]

METHODS AND RESULTS:
The anti-influenza viral activities of six stilbenoids from the lianas of Gnetum pendulum C. Y. Cheng were evaluated with two different assays, neuraminidase (NA) activity assay and cytopathic effect (CPE) reduction assay.
CONCLUSIONS:
The NA assay results showed that all six stilbenoids exerted an NA inhibitory effect, while the CPE assay indicated that among them, isorhapontigenin (2), gnetupendin B (3), Shegansu B (4), and gnetin D 6) exhibit significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 µg/mL in comparison to the positive controls oseltamivir acid and ribavirin whose IC(50) values were 0.040 and 5.54 µg/mL, respectively.
Shegansu B Description
Source: The herbs of Gnetum montanum Markgr.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9436 mL 9.7182 mL 19.4363 mL 38.8727 mL 48.5909 mL
5 mM 0.3887 mL 1.9436 mL 3.8873 mL 7.7745 mL 9.7182 mL
10 mM 0.1944 mL 0.9718 mL 1.9436 mL 3.8873 mL 4.8591 mL
50 mM 0.0389 mL 0.1944 mL 0.3887 mL 0.7775 mL 0.9718 mL
100 mM 0.0194 mL 0.0972 mL 0.1944 mL 0.3887 mL 0.4859 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2000;2(3):169-75.
A new stilbene dimer--shegansu B from Belamcanda chinensis.[Pubmed: 11256690]

METHODS AND RESULTS:
A new dimeric stilbene, named Shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectroscopic evidence including 2D-NMR studies.
CFN92592Bisisorhapontigenin A865474-98-2528.6C31H28O8
CFN92341Pallidol105037-88-5454.5C28H22O6
CFN92444Gnetulin152340-24-4514.5C30H26O8
CFN95146Leachianol G164204-62-0472.5C28H24O7
CFN95147Leachianol F164123-50-6472.5C28H24O7
CFN92340Ampelopsin F151487-08-0454.5C28H22O6
CFN95148Ampelopsin G151487-09-1680.7C42H32O9
CFN97075Alboctalol62394-00-7488.5 C28H24O8
CFN95781cis-epsilon-Viniferin62250-12-8454.5C28H22O6
CFN92854Viniferin253435-07-3454.1C28H22O6
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