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Taxcultine
Taxcultine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taxcultine
Price:
CAS No.: 153415-46-4
Catalog No.: CFN96640
Molecular Formula: C44H53NO14
Molecular Weight: 819.90 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The cell cultures of Taxus baccata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Taxcultine can actively promote tubulin assembly.
Taxcultine Description
Source: The cell cultures of Taxus baccata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2197 mL 6.0983 mL 12.1966 mL 24.3932 mL 30.4915 mL
5 mM 0.2439 mL 1.2197 mL 2.4393 mL 4.8786 mL 6.0983 mL
10 mM 0.122 mL 0.6098 mL 1.2197 mL 2.4393 mL 3.0492 mL
50 mM 0.0244 mL 0.122 mL 0.2439 mL 0.4879 mL 0.6098 mL
100 mM 0.0122 mL 0.061 mL 0.122 mL 0.2439 mL 0.3049 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1994 Jan;57(1):116-22.
New bioactive taxoids from cell cultures of Taxus baccata.[Pubmed: 7908950]

METHODS AND RESULTS:
Four new taxoids were isolated from cell cultures of Taxus baccata. Their structures were elucidated by spectroscopic analyses. Two were the aglycones corresponding to previously isolated 7-O-xylosides of taxol C [1] and 10-deacetyltaxol C [2]. The third [3] had an N-methylated side-chain, while the fourth, named Taxcultine [4], contained an n-propyl group on the side-chain.
CONCLUSIONS:
All four compounds actively promoted tubulin assembly. Taxol C [1] showed potent and selective cytotoxicity in the NCI human cell line screen.
Phytochemistry. 1996 Feb;41(3):803-5.
Isolation and semi-synthesis of a bioactive taxane from Taxus canadensis.[Pubmed: 8835457]
A minor bioactive taxane, isolated from the needles of Taxus canadensis and semi-synthesized, was shown to be Taxcultine.
Rutin

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Ginsenoside Rh3

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CAS No: 105558-26-7
Price: $218/5mg
Scutellarein

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CAS No: 529-53-3
Price: $60/20mg
Isoferulic acid

Catalog No: CFN98282
CAS No: 25522-33-2
Price: $50/20mg
Ptaquiloside

Catalog No: CFN80061
CAS No: 87625-62-5
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Scopolin

Catalog No: CFN98887
CAS No: 531-44-2
Price: $80/20mg
Isosilybin

Catalog No: CFN90260
CAS No: 72581-71-6
Price: $138/20mg
Angeloylgomisin H

Catalog No: CFN90710
CAS No: 66056-22-2
Price: $238/10mg
Piceatannol

Catalog No: CFN99024
CAS No: 10083-24-6
Price: $40/20mg
(+)-Isocorynoline

Catalog No: CFN90215
CAS No: 475-67-2
Price: $138/20mg
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