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Torachrysone 8-O-glucoside
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Torachrysone 8-O-glucoside
Price: $318 / 20mg
CAS No.: 64032-49-1
Catalog No.: CFN97101
Molecular Formula: C20H24O9
Molecular Weight: 408.4 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Yellow powder
Source: The rhizomes of Rheum officinale L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $100.6 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Torachryson-8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.
Targets: Antifection
In vitro:
Anal. Methods-UK. 2014, 6(10):3353-9.
The screening of potential α-glucosidase inhibitors from the Polygonum multiflorum extract using ultrafiltration combined with liquid chromatography-tandem mass spectrometry[Reference: WebLink]
α-Glucosidase inhibitors have been used for the management of type 2 diabetes (T2DM) for a long time. The natural α-glucosidase inhibitors from Chinese herbal medicine have become an attractive therapeutic approach for treating T2DM due to their low toxicity.
METHODS AND RESULTS:
In this study, a new kind of in vitro α-glucosidase inhibition assay based on using maltose as the substrate was developed, and this new established method was used to determine the α-glucosidase inhibitory activities of Polygonum multiflorum and four anthraquinone compounds. As a result, Polygonum multiflorum showed 50% α-glucosidase inhibition at the concentration of 0.0032 mg mL−1 and four anthraquinone compounds including emodin, aloe-emodin, physcion and rhein showed strong α-glucosidase inhibitory activities with IC50 values ranging from 4.12 μM to 5.68 μM, respectively. Moreover, the centrifugal ultrafiltration with LC-ESI-MSn was used to screen and identify active α-glucosidase inhibitors from Polygonum multiflorum extract and nine small-molecule active compounds were successfully identified as potential α-glucosidase inhibitors.
CONCLUSIONS:
Five compounds belonged to the anthraquinone group including emodin, physcion, aloe-emodin, rhein and physcion-8-O-glucoside, while the others were catechin, resveratrol, 2,3,5,4′-tetrahydroxystilbene-2-O-glucoside and Torachrysone 8-O-glucoside.
Torachrysone 8-O-glucoside Description
Source: The rhizomes of Rheum officinale L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

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Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4486 mL 12.2429 mL 24.4858 mL 48.9716 mL 61.2145 mL
5 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
10 mM 0.2449 mL 1.2243 mL 2.4486 mL 4.8972 mL 6.1214 mL
50 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
100 mM 0.0245 mL 0.1224 mL 0.2449 mL 0.4897 mL 0.6121 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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CAS No: 501-30-4
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Asperglaucide

Catalog No: CFN98937
CAS No: 56121-42-7
Price: $238/5mg
1-Acetyl-beta-carboline

Catalog No: CFN92122
CAS No: 50892-83-6
Price: $ / mg
Schisantherin D

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Price: $ / mg
Tricetin

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Jionoside A1

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