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Triangularine
Triangularine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Triangularine
Price:
CAS No.: 87340-27-0
Catalog No.: CFN00339
Molecular Formula: C18H25NO5
Molecular Weight: 335.40 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Senecio triangularis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Triangularine is a natural product from Senecio triangularis.
Triangularine Description
Source: The herbs of Senecio triangularis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9815 mL 14.9076 mL 29.8151 mL 59.6303 mL 74.5379 mL
5 mM 0.5963 mL 2.9815 mL 5.963 mL 11.9261 mL 14.9076 mL
10 mM 0.2982 mL 1.4908 mL 2.9815 mL 5.963 mL 7.4538 mL
50 mM 0.0596 mL 0.2982 mL 0.5963 mL 1.1926 mL 1.4908 mL
100 mM 0.0298 mL 0.1491 mL 0.2982 mL 0.5963 mL 0.7454 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Natural Products,1991 ,54 (3).
Gc-ms Determination of Pyrrolizidine Alkaloids in Four Senecio Species[Reference: WebLink]

METHODS AND RESULTS:
Four Senecio species were analyzed by gc-ms for their pyrrolizidine alkaloid content. This is the first published report of pyrrolizidine alkaloids in Senecio serra, Senecio dimorphophyllus, and Senecio hydrophyllus. Previously undetermined pyrrolizidine alkaloids from Senecio mikanioides were also tentatively identified. Gc-ms analyses showed the presence of the stereoisomers senecionine {9} and integerrimine {11} in S. dimorphophyllus and complex mixtures of monoester and diester pyrrolizidine alkaloids in the other three species. Tentative structural identifications were made of ten new pyrrolizidine alkaloids. These new alkaloids are isomers of Triangularine, sarracine {13}, 7-angelylplatynecine {5}, 7-angelylretronecine {2a}, and acetylated macronecine-type alkaloids.
CONCLUSIONS:
All three species contained both saturated and unsaturated pyrrolizidine alkaloids, and all had at least ten individual alkaloids. The mass spectral features and gc elution order of these compounds are discussed and the pyrolizidine alkaloid profiles of the plants are compared. The potential toxicity of the three species to range animals is discussed.
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