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Villosin C
Villosin C
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Villosin C
Price:
CAS No.: 160927-81-1
Catalog No.: CFN99676
Molecular Formula: C20H24O6
Molecular Weight: 360.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Yellow powder
Source: The herbs of Teucrium divaricatum ssp. villosum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Villosin C and villosin B have remarkable cytotoxic effects against four cancer cell lines (A549, HepG-2, MCF-7 and 4T1), with IC50 values ranging from 8.79 to 35.46 microM.
In vitro:
Nat Prod Commun. 2014 Jul;9(7):907-10.
Abietane diterpenoids from Clerodendrum trichotomum and correction of NMR data of Villosin C and B.[Pubmed: 25230490]

METHODS AND RESULTS:
Nine abietane diterpenoids (1-9) were isolated from the stems of Clerodendrum trichotomum Thunb. and identified by spectroscopic methods. Furthermore, corrected NMR data is provided for Villosin C (1) and B (2) whose absolute configurations were elucidated from circular dichroism (CD) data. All isolates were tested for cytotoxicity against four cancer cell lines (A549, HepG-2, MCF-7 and 4T1).
CONCLUSIONS:
Compounds 1, 2, 3, 4 and 8 were found to have remarkable cytotoxic effects with IC50 values ranging from 8.79 to 35.46 microM.
Villosin C Description
Source: The herbs of Teucrium divaricatum ssp. villosum
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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doi: 10.1016/j.molcel.2017.10.022.
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Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7747 mL 13.8735 mL 27.7469 mL 55.4939 mL 69.3674 mL
5 mM 0.5549 mL 2.7747 mL 5.5494 mL 11.0988 mL 13.8735 mL
10 mM 0.2775 mL 1.3873 mL 2.7747 mL 5.5494 mL 6.9367 mL
50 mM 0.0555 mL 0.2775 mL 0.5549 mL 1.1099 mL 1.3873 mL
100 mM 0.0277 mL 0.1387 mL 0.2775 mL 0.5549 mL 0.6937 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN95832Gerardianin A137171-31-4330.4C20H26O4
CFN99676Villosin C160927-81-1360.4 C20H24O6
CFN99463Teuvincenone H142299-73-8356.4 C20H20O6
CFN97587Uncinatone99624-92-7326.39C20H22O4
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