Zerumin A | CAS:176050-48-9 | Manufacturer ChemFaces

Zerumin A

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Description:

Zerumin A inhibits the proliferation and migration steps, to prevent angiogenesis progress.

Targets:

EGFR

In vitro:

Food Chemistry.2012 May;132(1):201–208.

Anti-angiogenic effects and mechanisms of zerumin A from Alpinia caerulea.[Reference: WebLink]

Two diterpenoids were isolated and identified as Zerumin A and (E)-8(17),12-labdadiene-15,16-dial.
METHODS AND RESULTS:
Zerumin A, which had mainly accumulated in the fruits and bearing a carboxylic group, could dose-dependently inhibit vessel formation, in both wild-type and Tg(fli1a:EGFP)y1 zebrafish embryos.Further investigation, by human umbilical vein endothelial cell assays, revealed that Zerumin A specifically inhibited the proliferation and migration steps, to prevent angiogenesis progress.

Zerumin A Description

Source:	The rhizomes of Curcuma longa L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Zerumin A
Price:
CAS No.:	176050-48-9
Catalog No.:	CFN92779
Molecular Formula:	C₂₀H₃₀O₃
Molecular Weight:	318.5 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	Powder
Source:	The rhizomes of Curcuma longa L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Cytotoxic Compound Library Antiangiogenic Compound Library Diterpenoids Compound Library EGFR Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.1397 mL	15.6986 mL	31.3972 mL	62.7943 mL	78.4929 mL
5 mM	0.6279 mL	3.1397 mL	6.2794 mL	12.5589 mL	15.6986 mL
10 mM	0.314 mL	1.5699 mL	3.1397 mL	6.2794 mL	7.8493 mL
50 mM	0.0628 mL	0.314 mL	0.6279 mL	1.2559 mL	1.5699 mL
100 mM	0.0314 mL	0.157 mL	0.314 mL	0.6279 mL	0.7849 mL

CFN92778	Coronadiene	1145689-64-0	262.4	C₁₇H₂₆O₂
CFN99058	15-Nor-14-oxolabda-8(17),12-dien-18-oic acid	1039673-32-9	304.4	C₁₉H₂₈O₃
CFN89382	Junicedric acid	41787-69-3	336.46	C₂₀H₃₂O₄
CFN92779	Zerumin A	176050-48-9	318.5	C₂₀H₃₀O₃
CFN97091	Alepterolic acid	63399-38-2	320.5	C₂₀H₃₂O₃
CFN97090	3-Acetoxy-8(17),13E-labdadien-15-oic acid	63399-37-1	362.5	C₂₂H₃₄O₄
CFN89391	ent-3beta,18-Dihydroxylabda-8(17),13E-dien-15-oic acid	99624-39-2	336.46	C₂₀H₃₂O₄
CFN99412	9-Hydroxy-13E-labden-15-oic acid	132915-47-0	322.5	C₂₀H₃₄O₃
CFN99303	Coronarin B	119188-38-4	334.5	C₂₀H₃₀O₄
CFN96361	Metasequoic acid A	113626-22-5	302.5	C₂₀H₃₀O₂