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Zeylasteral
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Product Name Zeylasteral
Price:
CAS No.: 87064-16-2
Catalog No.: CFN92084
Molecular Formula: C30H38O6
Molecular Weight: 494.6 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Tripterygium wilfordii Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes. Zeylasteral and demethylZeylasteral have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans.
Targets: Antifection
In vitro:
Planta Med. 2005 Apr;71(4):313-9.
Antimicrobial activity of 6-oxophenolic triterpenoids. Mode of action against Bacillus subtilis.[Pubmed: 15856406]
Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes, which have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans.
METHODS AND RESULTS:
The time-kill curves for Zeylasteral and demethylZeylasteral at concentrations twice their MICs, against Bacillus subtilis showed that the colony forming units were reduced in 3-log10 and > 4-log10 respectively. This reduction was dependent on inoculum size and the growth phase of cells, and was greater when the compounds were incorporated in the exponential phase, indicating a bacteriolytic effect. Treatment with both agents, particularly with Zeylasteral (20 microg/mL) caused a reduction of optical density at 550 nm. With regard to the synthesis of DNA, RNA, protein and cell wall, the compounds exhibited the fastest inhibition against cell wall synthesis.
CONCLUSIONS:
Thus, the predisposition to lysis, the morphological changes seen by microscopy, and the complete inhibition in the incorporation the N-acetyl-d-[1 - 14C]glucosamine, suggest that the phenolic compounds compromise the cell wall synthesis and/or cytoplasmic membrane.
Zeylasteral Description
Source: The herbs of Tripterygium wilfordii Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0218 mL 10.1092 mL 20.2184 mL 40.4367 mL 50.5459 mL
5 mM 0.4044 mL 2.0218 mL 4.0437 mL 8.0873 mL 10.1092 mL
10 mM 0.2022 mL 1.0109 mL 2.0218 mL 4.0437 mL 5.0546 mL
50 mM 0.0404 mL 0.2022 mL 0.4044 mL 0.8087 mL 1.0109 mL
100 mM 0.0202 mL 0.1011 mL 0.2022 mL 0.4044 mL 0.5055 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Pinoresinol diglucoside

Catalog No: CFN99994
CAS No: 63902-38-5
Price: $100/20mg
Pinostrobin chalcone

Catalog No: CFN99878
CAS No: 18956-15-5
Price: $368/20mg
Muscone

Catalog No: CFN99518
CAS No: 541-91-3
Price: $30/20mg
Procyanidin B2

Catalog No: CFN99558
CAS No: 29106-49-8
Price: $138/20mg
Ginsenoside Compound K

Catalog No: CFN99756
CAS No: 39262-14-1
Price: $30/20mg
Paeonol

Catalog No: CFN98926
CAS No: 552-41-0
Price: $30/20mg
Dimethylacrylshikonin

Catalog No: CFN90164
CAS No: 24502-79-2
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3-Isomangostin

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Camelliaside A

Catalog No: CFN93559
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Price: $318/20mg
Niga-ichigoside F1

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Price: $318/20mg
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